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KIAA0586 Products

(KIAA0586)

Categories

Required for ciliogenesis and sonic hedgehog/SHH signaling (PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation (By similarity). Involved in regulation of cell intracellular organization (PubMed:26386247). Involved in regulation of cell polarity (By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles (PubMed:25251415). {ECO:0000250|UniProtKB:Q1G7G9, ECO:0000269|PubMed:21750036, ECO:0000269|PubMed:25251415, ECO:0000269|PubMed:26386247}.

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Recommended KIAA0586 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
Cat. No. ABIN7115666
Quantity 100 μg
Datasheet Datasheet

Recommended KIAA0586 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6234290
Quantity 96 tests
Datasheet Datasheet

Synonyms and alternative names related to KIAA0586

KIAA0586 (KIAA0586), Talpid3

Protein level used designations for KIAA0586

  • ortholog of chicken talpid{3}
  • protein TALPID3
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