Insulin ELISA Kit
Quick Overview for Insulin ELISA Kit (ABIN1326860)
Target
See all Insulin (INS) ELISA KitsReactivity
Detection Method
Method Type
Application
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Analytical Method
- Quantitative
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Storage
- 4 °C
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: "Androgenetic alopecia, metabolic syndrome, and insulin resistance: Is there any association? A case-control study." in: Indian dermatology online journal, Vol. 5, Issue 3, pp. 276-81, (2014) (PubMed).
: "Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets." in: PLoS ONE, Vol. 9, Issue 3, pp. e90519, (2014) (PubMed).
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: "Androgenetic alopecia, metabolic syndrome, and insulin resistance: Is there any association? A case-control study." in: Indian dermatology online journal, Vol. 5, Issue 3, pp. 276-81, (2014) (PubMed).
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- Insulin (INS)
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Alternative Name
- Insulin
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Background
- Insulin is the principal hormone responsible for the control of glucose metabolism. It is synthesized in the _-cells of the islets of Langerhans as the precursor, proinsulin, which is processed to form C-peptide and insulin. Both are secreted in equimolar amounts into the portal circulation. The mature insulin molecule comprises two polypeptide chains, the A chain and B chain (21 and 30 amino acids respectively). The two chains are linked together by two inter-chain disulphide bridges. There is also an intra-chain disulphide bridge in the A chain. Insulin concentrations are severely reduced in insulin-dependent diabetes mellitus (IDDM) and some other conditions such as hypopituitarism. Insulin levels are raised in non-insulin-dependent diabetes mellitus (NIDDM), obesity, insulinoma and some endocrine dysfunctions such as Cushing
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Pathways
- NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target See all Insulin (INS) ELISA Kits
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