(4 references)-
- Target See all ACE2 Kits
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- Detection Method
- Fluorometric
- Application
- Activation (Act), Fluorescence Resonance Energy Transfer Microscopy (FRET)
- Brand
- SensoLyte®
- Characteristics
- The SensoLyte® 390 ACE2 Activity Assay Kit provides a convenient assay for high throughput screening of ACE2 enzyme inhibitors and inducers using a Mc-Ala/Dnp fluorescence resonance energy transfer (FRET) peptide. In the FRET peptide, the fluorescence of Mc-Ala is quenched by Dnp. Upon cleavage into two separate fragments by ACE2, the fluorescence of Mc-Ala is recovered, and can be monitored at excitation/emission = 330/390 nm. This assay can detect the activity of subnanogram level of ACE2. Assays are performed in a convenient 96-well microplate format.
- Top Product
- Discover our top product ACE2 ELISA Kit
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Angiotensin I Converting Enzyme 2 (ACE2) ELISA Kit
ACE2 Reactivity: Rat Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Plasma, Serum
Angiotensin I Converting Enzyme 2 (ACE2) ELISA KitACE2 Reactivity: Rat Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Plasma, Serum, Tissue Homogenate
Angiotensin I Converting Enzyme 2 (ACE2) ELISA KitACE2 Reactivity: Human Colorimetric Sandwich ELISA 0.391 ng/mL - 25 ng/mL Plasma, Serum, Tissue Homogenate
Angiotensin I Converting Enzyme 2 (ACE2) ELISA KitACE2 Reactivity: Mouse Colorimetric Sandwich ELISA 12.5 pg/mL - 800 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Angiotensin I Converting Enzyme 2 (ACE2) ELISA KitACE2 Reactivity: Mouse AA 18-740 Colorimetric Sandwich ELISA 62.5-4000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Angiotensin I Converting Enzyme 2 (ACE2) ELISA KitACE2 Reactivity: Human Colorimetric Sandwich ELISA 0.025 ng/mL - 20 ng/mL Cell Culture Cells, Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Lysate
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- Comment
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FRET-based Assay Kit
- Restrictions
- For Research Use only
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- Handling Advice
- Protect Components A and B from light and from moisture.
- Storage
- -20 °C
- Storage Comment
- Store all kit components at -20 °C. Components C and E can be stored at room temperature for convenience.
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: "Conversion of A?43 to A?40 by the successive action of angiotensin-converting enzyme 2 and angiotensin-converting enzyme." in: Journal of neuroscience research, Vol. 92, Issue 9, pp. 1178-86, (2014) (PubMed).
: "Angiotensin-(1-7) augments endothelium-dependent relaxations of porcine coronary arteries to bradykinin by inhibiting angiotensin-converting enzyme 1." in: Journal of cardiovascular pharmacology, Vol. 63, Issue 5, pp. 453-60, (2014) (PubMed).
: "Gestational protein restriction increases angiotensin II production in rat lung." in: Biology of reproduction, Vol. 88, Issue 3, pp. 64, (2013) (PubMed).
: "Activities of angiotensin-converting enzymes ACE1 and ACE2 and inhibition by bioactive peptides in porcine ocular tissues." in: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, Vol. 25, Issue 1, pp. 23-8, (2009) (PubMed).
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: "Conversion of A?43 to A?40 by the successive action of angiotensin-converting enzyme 2 and angiotensin-converting enzyme." in: Journal of neuroscience research, Vol. 92, Issue 9, pp. 1178-86, (2014) (PubMed).
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- Target
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- Alternative Name
- ACE2 (ACE2 Products)
- Synonyms
- ACE1 Kit, CD143 Kit, DCP Kit, DCP1 Kit, ICH Kit, MVCD3 Kit, ACEH Kit, 2010305L05Rik Kit, zgc:92514 Kit, angiotensin I converting enzyme Kit, angiotensin I converting enzyme 2 Kit, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Kit, ACE Kit, ACE2 Kit, Ace2 Kit, ace2 Kit
- Background
- ACE2 or ACEH, angiotensin-converting enzyme 2, a homolog of angiotensin-converting enzyme, is a novel zinc metallopeptidase with specificity, tissue distribution, and function distinct from those of ACE. ACE2 may play a unique role in the renin-angiotensin system and mediate cardiovascular and renal function.
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