Clusterin ELISA Kit
Quick Overview for Clusterin ELISA Kit (ABIN2042407)
Target
See all Clusterin (CLU) ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
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Minimum Detection Limit
- 0.8 ng/mL
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Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensitivity
- < 20 pg/mL
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Components
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96-well plate pre-coated with anti-Clusterin, Human
Lyophilized recombinant Clusterin, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Plate
- Pre-coated
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Protocol
- Sandwich ELISA quantitative detection kit for Human Clusterin in cell culture supernates, serum, plasma (heparin, EDTA), saliva and urine.Clusterin (apolipoprotein J) is a 75 - 80kD disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis.[1] In humans, clusterin is encoded by the CLU gene.This protein has several synonyms dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI). Clusterin was mapped to mouse chromosome 14. Clusterin is a ubiquitously expressed molecule thought to influence a variety of processes including cell death. In the brain, it accumulates in dying neurons following seizures and hypoxic-ischemic (H-I) injury. clusterin may be a new therapeutic target to modulate non-caspase-dependent neuronal death following acute brain injury.
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Restrictions
- For Research Use only
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Storage
- 4 °C/-20 °C
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- Clusterin (CLU)
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Alternative Name
- Clusterin
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Gene ID
- 1191
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UniProt
- P10909
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Pathways
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
Target See all Clusterin (CLU) ELISA Kits
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