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Leptin Receptor ELISA Kit

Mouse Leptin Receptor ELISA Kit Colorimetric assay for quantification of Mouse Leptin Receptor.
Catalog No. ABIN2042578

Quick Overview for Leptin Receptor ELISA Kit (ABIN2042578)

Target

See all Leptin Receptor (LEPR) ELISA Kits
Leptin Receptor (LEPR)

Reactivity

  • 8
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Mouse

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Detection Range

6-10000 pg/mL

Application

ELISA
  • Minimum Detection Limit

    6 pg/mL

    Cross-Reactivity (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensitivity

    < 5 pg/mL

    Components

    96-well plate pre-coated with anti-Leptin receptor, Mouse
    Lyophilized recombinant Leptin receptor, Mouse standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plate

    Pre-coated

    Protocol

    Sandwich ELISA quantitative detection kit for Mouse Leptin receptor in cell culture supernates, serum and plasma (heparin, EDTA).Leptin receptor (or Obese receptor, OBR) is a single membrane-spanning receptor most related to the gp130 signal-transducing component of the IL-6 receptor, the G-CSF receptor, and the LIF receptor. OB-R mRNA is expressed not only in choroid plexus, but also in several other tissues, including hypothalamus.1 Leptin acts through the leptin receptor, a single-transmembrane domain receptor of the cytokine-receptor family.2 Leptin controls energy balance and food intake through the leptin receptor in the hypothalamus of the brain, which suggests that some polymorphisms of the leptin receptor gene (LEPR) might contribute to obesity or obesity-related diseases.3 Leptin is also involved in the regulation of blood pressure through the leptin receptor.4

    Restrictions

    For Research Use only
  • Storage

    4 °C/-20 °C
  • Target See all Leptin Receptor (LEPR) ELISA Kits

    Leptin Receptor (LEPR)

    Alternative Name

    Leptin Receptor

    Gene ID

    16847

    UniProt

    P48356

    Pathways

    JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour
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