TEK ELISA Kit
Quick Overview for TEK ELISA Kit (ABIN2042672)
Target
See all TEK ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
-
-
Minimum Detection Limit
- 5 pg/mL
-
Cross-Reactivity (Details)
- There is no detectable cross-reactivity with other relevant proteins.
-
Sensitivity
- < 10 pg/mL
-
Components
-
96-well plate pre-coated with anti-TEK/TIE2, Mouse
Lyophilized recombinant TEK/TIE2, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
-
-
-
-
Plate
- Pre-coated
-
Protocol
- Sandwich ELISA quantitative detection kit for Mouse TEK/TIE2 in cell culture supernates, tissue homogenates, serum and plasma (heparin, EDTA).Angiopoietin-1 receptor, also called TEK or TIE2 is a protein that in humans is encoded by the TEK gene. This gene is mapped to 9p21.2. The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
-
Restrictions
- For Research Use only
-
-
-
Storage
- 4 °C/-20 °C
-
-
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
-
Alternative Name
- TEK/TIE2
-
Gene ID
- 21687
-
UniProt
- Q02858
-
Pathways
- RTK Signaling, Growth Factor Binding
Target See all TEK ELISA Kits
-