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Granulin ELISA Kit

GRN Reactivity: Mouse Colorimetric Sandwich ELISA 0.125-8 ng/mL Cell Culture Supernatant, Serum
Catalog No. ABIN2745482
  • Target See all Granulin (GRN) ELISA Kits
    Granulin (GRN)
    Reactivity
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Detection Range
    0.125-8 ng/mL
    Minimum Detection Limit
    0.125 ng/mL
    Application
    ELISA
    Sample Type
    Cell Culture Supernatant, Serum
    Analytical Method
    Quantitative
    Specificity
    Detects mouse progranulin.
    Cross-Reactivity
    Mouse (Murine)
    No Cross-Reactivity
    Human
    Cross-Reactivity (Details)
    Does not cross-react with human progranulin.
    Sensitivity
    60 pg/mL
    Characteristics
    Progranulin (mouse) ELISA Kit
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  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: +4°C
    12 months after the day of manufacturing. See expiry date on ELISA Kit box.
  • Target See all Granulin (GRN) ELISA Kits
    Granulin (GRN)
    Alternative Name
    Progranulin (GRN Products)
    Synonyms
    GRN ELISA Kit, grn ELISA Kit, wu:fb11g12 ELISA Kit, wu:fj18f05 ELISA Kit, MGC53354 ELISA Kit, DKFZp459H066 ELISA Kit, CLN11 ELISA Kit, GEP ELISA Kit, GP88 ELISA Kit, PCDGF ELISA Kit, PEPI ELISA Kit, PGRN ELISA Kit, epithelin ELISA Kit, acrogranin ELISA Kit, granulin precursor ELISA Kit, granulin a ELISA Kit, Granulins ELISA Kit, granulin L homeolog ELISA Kit, granulin ELISA Kit, GRN ELISA Kit, grna ELISA Kit, grn ELISA Kit, grn.L ELISA Kit, granulin ELISA Kit, ORF1 granulin ELISA Kit, Grn ELISA Kit
    Target Type
    Viral Protein
    Background
    Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer's disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
    UniProt
    P28798
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