RBP4 ELISA Kit
Quick Overview for RBP4 ELISA Kit (ABIN2745487)
Target
See all RBP4 ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
Sample Type
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Minimum Detection Limit
- 0.001 μg/mL
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Analytical Method
- Quantitative
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Specificity
- Detects human RBP4.
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Cross-Reactivity
- Human
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Cross-Reactivity (Details)
- Does not cross-react with human adiponectin, human resistin or human RELM-beta.
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Sensitivity
- 1 ng/mL
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Characteristics
- RBP4 (human) Competitive ELISA Kit
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Storage
- 4 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.
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- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
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Alternative Name
- RBP4
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Background
- Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function and recent studies have shown an association between serum RBP4 levels and urinary albumin excretion. The urinary RBP4 concentration may be a valuable marker for both, insulin resistance and microalbuminuria in insulin-resistant subjects.
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UniProt
- P02753
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Pathways
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
Target See all RBP4 ELISA Kits
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