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CXCL2 ELISA Kit

This Colorimetric ELISA kit is designed for the quantitative measurement of Rat CXCL2.
Catalog No. ABIN4987025
$548.90
Plus shipping costs $50.00
96 tests
Shipping to: United States
Delivery in 6 to 8 Business Days

Quick Overview for CXCL2 ELISA Kit (ABIN4987025)

Target

See all CXCL2 ELISA Kits
CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Reactivity

  • 13
  • 9
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  • 2
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Rat

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Detection Range

0.03-2.0 ng/mL

Application

ELISA

Sample Type

Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
  • Minimum Detection Limit

    0.03 ng/mL

    Analytical Method

    Quantitative

    Specificity

    Natural and recombinant Rat MIP-2 Ligand

    Sensitivity

    15 pg/mL

    Material not included

    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
  • Application Notes

    Detection Wavelength: 450 nm

    Sample Volume

    20 μL

    Assay Time

    3 h

    Plate

    Pre-coated

    Restrictions

    For Research Use only
  • Storage

    4 °C
  • Target See all CXCL2 ELISA Kits

    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

    Alternative Name

    MIP-2

    Background

    Macrophage inflammatory protein-2(MIP-2) was originally identified as a heparinbinding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The protein is produced by a variety of cell types, including intestinal epithelium, macrophages, astrocytes and fibroblasts. Homologs of the mouse MIP-2 have been identified in human, rat and cotton rat. MIP-2 is an ELR-containing member of the alpha (CXC) subfamily of chemokines. The cotton rat MIP-2 gene encodes a 101 amino acid (aa) residue precursor protein with a 28 aa putative signal peptide that is cleaved to generate the 73 aa mature protein. Mature cotton rat MIP-2 has two intrachain disulfide bonds and no potential glycosylation sites. It shares approximately 79 % and 85 % aa sequence identity with rat CINC-3 and mouse MIP-2, respectively. MIP-2 is a potent neutrophil attractant and activator. MIP-2 binds and activates the chemokine receptor CXCR-2. The recombinant cotton rat MIP-2 has been shown to bind and activate the human CXCR-2.

    Pathways

    Cellular Response to Molecule of Bacterial Origin
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