CXCL2 ELISA Kit
Quick Overview for CXCL2 ELISA Kit (ABIN4987025)
Target
See all CXCL2 ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
Sample Type
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Minimum Detection Limit
- 0.03 ng/mL
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Analytical Method
- Quantitative
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Specificity
- Natural and recombinant Rat MIP-2 Ligand
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Sensitivity
- 15 pg/mL
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Material not included
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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Application Notes
- Detection Wavelength: 450 nm
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Sample Volume
- 20 μL
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Assay Time
- 3 h
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Storage
- 4 °C
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- CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
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Alternative Name
- MIP-2
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Background
- Macrophage inflammatory protein-2(MIP-2) was originally identified as a heparinbinding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The protein is produced by a variety of cell types, including intestinal epithelium, macrophages, astrocytes and fibroblasts. Homologs of the mouse MIP-2 have been identified in human, rat and cotton rat. MIP-2 is an ELR-containing member of the alpha (CXC) subfamily of chemokines. The cotton rat MIP-2 gene encodes a 101 amino acid (aa) residue precursor protein with a 28 aa putative signal peptide that is cleaved to generate the 73 aa mature protein. Mature cotton rat MIP-2 has two intrachain disulfide bonds and no potential glycosylation sites. It shares approximately 79 % and 85 % aa sequence identity with rat CINC-3 and mouse MIP-2, respectively. MIP-2 is a potent neutrophil attractant and activator. MIP-2 binds and activates the chemokine receptor CXCR-2. The recombinant cotton rat MIP-2 has been shown to bind and activate the human CXCR-2.
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target See all CXCL2 ELISA Kits
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