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BMP4 ELISA Kit

BMP4 Reactivity: Monkey AA 293-408 Colorimetric Sandwich ELISA
Catalog No. ABIN5510537
  • Target See all BMP4 ELISA Kits
    BMP4 (Bone Morphogenetic Protein 4 (BMP4))
    Binding Specificity
    AA 293-408
    Reactivity
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Monkey
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Application
    ELISA
    Purpose
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate BMP-4
    Brand
    PicoKine™
    Analytical Method
    Quantitative
    Specificity
    Expression system for standard: NSO
    Immunogen sequence: S293-R408
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Characteristics

    Sequence similarities: Belongs to the TGF-beta family.

    Tissue Specificity: Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.

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  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Expiry Date
    12 months
  • Target See all BMP4 ELISA Kits
    BMP4 (Bone Morphogenetic Protein 4 (BMP4))
    Alternative Name
    BMP4 (BMP4 Products)
    Synonyms
    BMP2B ELISA Kit, BMP2B1 ELISA Kit, MCOPS6 ELISA Kit, OFC11 ELISA Kit, ZYME ELISA Kit, Bmp-4 ELISA Kit, Bmp2b ELISA Kit, Bmp2b-1 ELISA Kit, Bmp2b1 ELISA Kit, BOMPR4A ELISA Kit, bmp-4 ELISA Kit, zbmp-4 ELISA Kit, zgc:100779 ELISA Kit, BMP-4 ELISA Kit, XBMP-4 ELISA Kit, bmp2b ELISA Kit, bmp2b1 ELISA Kit, bmp4 ELISA Kit, ofc11 ELISA Kit, xbmp4 ELISA Kit, zyme ELISA Kit, BMP4 ELISA Kit, bone morphogenetic protein 4 ELISA Kit, bone morphogenetic protein 4 L homeolog ELISA Kit, bone morphogenetic protein 4 S homeolog ELISA Kit, BMP4 ELISA Kit, Bmp4 ELISA Kit, bmp4 ELISA Kit, bmp4.L ELISA Kit, bmp4.S ELISA Kit
    Background

    Protein Function: Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). .

    Background: Bone morphogenetic protein 4 is a protein that in humans is encoded by the BMP4 gene which is located to 14q22-q23.1, The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. BMP4 is a polypeptide belonging to the TGF-beta superfamily of proteins. It, like other bone morphogenetic proteins, is involved in bone and cartilage development, specifically tooth and limb development and fracture repair. It has been shown to be involved in muscle development, bone mineralization, and uteric bud development. BMP4 has also been implicated in Fibrodysplasia Ossificans Progressiva in which it is underexpressed. In monkey primate embryonic development, BMP4 is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog(released from the ventral portion of the notochord) to establish a dorsal-ventral axis for the differentiation of later structures. BMP4 stimulates differentiation of overlying ectodermal tissue. Inhibition of the BMP4 signal(by chordin, noggin, or follistatin) causes the ectoderm to differentiate into the neural plate. The standard product used in this kit is recombinant BMP-4 with the molecular mass of 26KDa.

    Synonyms: Bone morphogenetic protein 4,BMP-4,Bone morphogenetic protein 2B,BMP-2B,BMP4,BMP2B, DVR4,

    Full Gene Name: Bone morphogenetic protein 4

    Cellular Localisation: Secreted, extracellular space, extracellular matrix.
    UniProt
    P12644
    Pathways
    Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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