CCL27 ELISA Kit

Catalog No. ABIN5510583

Product Details CCL27 ELISA Kit

Target: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Binding Specificity: AA 26-120

Reactivity: Mouse

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse CCL27/CTACK

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: E.coli
Immunogen sequence: L26-N120

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Isoform 1 is predominantly expressed in placenta and weakly in skin. Isoform 2 is predominantly expressed in testes and brain, weakly in kidney and liver and even lower in heart and muscle. Low expression of both isoforms in other tissues.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for CCL27

Target: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Alternative Name: Ccl27 (CCL27 Products)

Synonyms: ALP ELISA Kit, ILC ELISA Kit, CTACK ELISA Kit, ESkine ELISA Kit, CCL27 ELISA Kit, CTAK ELISA Kit, ESKINE ELISA Kit, PESKY ELISA Kit, SCYA27 ELISA Kit, AW558992 ELISA Kit, Ccl27 ELISA Kit, Scya27 ELISA Kit, Scya27a ELISA Kit, C-C motif chemokine ligand 27 ELISA Kit, uncharacterized LOC508933 ELISA Kit, chemokine (C-C motif) ligand 27A ELISA Kit, Ccl27 ELISA Kit, CCL27 ELISA Kit, LOC508933 ELISA Kit, Ccl27a ELISA Kit

Background:

Protein Function: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10.

Background: Chemokine (C-C motif) ligand 27 (CCL27) is a small cytokine belonging to the CC chemokine family, it is also known under the names IL-11 R-alpha-locus chemokine (ILC), Skinkine, ESkine and Cutaneous T-cell-attracting chemokine (CTACK). The human gene is mapped to 9p13.3. CCL27 is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediatedinflammation of the skin. And CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin. It elicits its chemotacticeffects by binding to the chemokine receptor CCR10.

Synonyms: C-C motif chemokine 27,CC chemokine ILC,Cutaneous T-cell-attracting chemokine,CTACK,ESkine,IL-11 R-alpha-locus chemokine,ALP,mILC,Skinkine,Small-inducible cytokine A27,Ccl27,Ilc, Scya27,

Full Gene Name: C-C motif chemokine 27

Cellular Localisation: Isoform 1: Secreted . Nucleus . May also be nuclear when following receptor (CCR10)-mediated internalization..

UniProt: Q9Z1X0