TGFB3 ELISA Kit

Catalog No. ABIN5510619

Product Details TGFB3 ELISA Kit

Target: TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

Binding Specificity: AA 301-412

Reactivity: Rabbit

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of activated rabbit TGF-beta 3

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: sf21
Immunogen sequence: A301-S412

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Sequence similarities: Belongs to the TGF-beta family.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for TGFB3

Target: TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

Alternative Name: TGFB3 (TGFB3 Products)

Synonyms: TGFB3 ELISA Kit, ARVD ELISA Kit, TGF-beta3 ELISA Kit, Tgfb-3 ELISA Kit, TGF-B3 ELISA Kit, TGFbeta3 ELISA Kit, wu:fc78g09 ELISA Kit, zgc:92058 ELISA Kit, transforming growth factor beta 3 ELISA Kit, transforming growth factor, beta 3 ELISA Kit, TGFB3 ELISA Kit, Tgfb3 ELISA Kit, tgfb3 ELISA Kit

Background:

Protein Function: Involved in embryogenesis and cell differentiation.

Background: Transforming growth factor beta 3(TGF-beta 3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily. TGF-beta 3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix(ECM) formation during the process of palate development. Without TGF-beta 3, mammals develop a deformity known as acleft palate. This is caused by failure of epithelial cells in both sides of the developing palate to fuse. TGF-beta 3 also plays an essential role in controlling the development of lungs in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. TGF-beta 3 activated Lef1 in the absence of beta-catenin(CTNNB1) via nuclear phospho-Smad2 and Smad4.

Synonyms: Transforming growth factor beta-3,TGF-beta-3,Latency-associated peptide,LAP,TGFB3,

Full Gene Name: Transforming growth factor beta-3

Cellular Localisation: Secreted.

UniProt: P10600

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus