SERPINA7 ELISA Kit

Catalog No. ABIN5510681

Product Details SERPINA7 ELISA Kit

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Binding Specificity: AA 21-415

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Serpin A7

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: NSO
Immunogen sequence: A21-A415

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Characteristics:

Tissue Specificity: Expressed by the liver and secreted in plasma.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Alternative Name: SERPINA7 (SERPINA7 Products)

Synonyms: C730040N12Rik ELISA Kit, Tbg ELISA Kit, TBG ELISA Kit, THYROXINE-BINDING GLOBULIN ELISA Kit, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 ELISA Kit, serpin family A member 7 ELISA Kit, Serpina7 ELISA Kit, SERPINA7 ELISA Kit

Background:

Protein Function: Major thyroid hormone transport protein in serum.

Background: Thyroxine-binding globulin (TBG), also known as SERPINA7, is the major thyroid hormone transport protein in serum. There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. Using DNA blot hybridization, it is detected that there is a single-copy TBG gene located on the long arm of the X chromosome.

Synonyms: Thyroxine-binding globulin,Serpin A7,T4-binding globulin,SERPINA7,TBG,

Full Gene Name: Thyroxine-binding globulin

Cellular Localisation: Secreted.

UniProt: P05543

Pathways: Hormone Transport