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Sclerostin ELISA Kit

SOST Reactivity: Rat AA 29-213 Colorimetric Sandwich ELISA
Catalog No. ABIN5510722
  • Target See all Sclerostin (SOST) ELISA Kits
    Sclerostin (SOST)
    Binding Specificity
    AA 29-213
    Reactivity
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Application
    ELISA
    Purpose
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat Sclerostin/SOST
    Brand
    PicoKine™
    Analytical Method
    Quantitative
    Specificity
    Expression system for standard: NSO
    Immunogen sequence: F29-Y213
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
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  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Expiry Date
    12 months
  • Target See all Sclerostin (SOST) ELISA Kits
    Sclerostin (SOST)
    Alternative Name
    Sost (SOST Products)
    Background

    Protein Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. .

    Background: Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally, Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21.

    Synonyms: Sclerostin,Sost,

    Full Gene Name: Sclerostin

    Cellular Localisation: Secreted.
    UniProt
    Q99P67
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