PTH ELISA Kit
Quick Overview for PTH ELISA Kit (ABIN996928)
Target
See all PTH ELISA KitsReactivity
Detection Method
Method Type
Application
Sample Type
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Purpose
- Intact-PTH ELISA is intended for the quantitative determination of IntactPTH (Parathyroid Hormone) in human serum.
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Analytical Method
- Quantitative
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Specificity
- 100 %
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Sensitivity
- 1.72 pg/mL
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Parathyroid Hormone (PTH) ELISA Kit
PTH Reactivity: Mouse Colorimetric Competition ELISA 9.88 pg/mL - 800 pg/mL Plasma, Serum
Parathyroid Hormone (PTH) ELISA KitPTH Reactivity: Rat Colorimetric Competition ELISA 9.88 pg/mL - 800 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Parathyroid Hormone (PTH) ELISA KitPTH Reactivity: Human Colorimetric Competition ELISA 12.35 pg/mL - 1000 pg/mL Plasma, Serum
Parathyroid Hormone (PTH) ELISA KitPTH Reactivity: Rat Colorimetric Sandwich ELISA 15.63 pg/mL - 1000 pg/mL Cell Culture Supernatant, Plasma, Serum
Parathyroid Hormone (PTH) ELISA KitPTH Reactivity: Mouse Colorimetric Sandwich ELISA 15.63 pg/mL - 1000 pg/mL Cell Culture Supernatant, Plasma, Serum
Parathyroid Hormone (PTH) ELISA KitPTH Reactivity: Dog Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Parathyroid Hormone (PTH) ELISA KitPTH Reactivity: Rabbit Colorimetric Sandwich ELISA 7.8 pg/mL - 500 pg/mL Plasma, Serum
Parathyroid Hormone (PTH) ELISA KitPTH Reactivity: Mouse Colorimetric Sandwich ELISA 15.625 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Parathyroid Hormone (PTH) ELISA KitPTH Reactivity: Rat Colorimetric Sandwich ELISA 15.625 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Parathyroid Hormone (PTH) ELISA KitPTH Reactivity: Cow Colorimetric Sandwich ELISA 15.625 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
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Sample Volume
- 25 μL
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Assay Time
- 3 - 4 h
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Storage
- 4 °C
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Expiry Date
- 12 months
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- PTH (Parathyroid Hormone (PTH))
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Background
- PTH (Parathyroid hormone, Parathormone, Parathyrin) is biosynthesized in the parathyroid gland as a pre-proparathyroid hormone, a larger molecular precursor consisting of 115 amino acids. Following sequential intracellular cleavage of a 25-amino acid sequence, preproparathyroid hormone is converted to an intermediate, a 90-amino acid polypeptide, proparathyroid hormone. With additional proteolytic modification, proparathyroid hormone is then converted to parathyroid hormone, an 84 amino acid polypeptide. In healthy individuals, regulation of parathyroid hormone secretion normally occurs via a negative feedback action of serum calcium on the parathyroid glands. Intact PTH is biologically active and clears very rapidly from the circulation with a half-life of less than four minutes. PTH undergoes proteolysis in the parathyroid glands, but mostly peripherally, particularly in the liver but also in the kidneys and bone, to give N-terminal fragments and longer lived C-terminal and mid-region fragments. In subjects with renal insufficiency, C-terminal and mid-region PTH assays typically give elevated PTH results, as reflected by impaired renal clearance.
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Pathways
- cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
Target See all PTH ELISA Kits
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