Helicobacter Pylori IgA (Hp IgA) ELISA Kit

Catalog No. ABIN997007

This Colorimetric ELISA kit is designed for the quantitative measurement of Human Helicobacter Pylori IgA.

Quick Overview for Helicobacter Pylori IgA (Hp IgA) ELISA Kit (ABIN997007)

Target: Helicobacter Pylori IgA (Hp IgA)

Reactivity: Human

Detection Method: Colorimetric

Method Type: Competition ELISA

Application: ELISA

Sample Type: Serum

Product Details

Purpose: Helicobacter pylori IgA is intended for use in evaluating the serologic status to H. pylori infection in patients with gastrointestinal symptoms.

Analytical Method: Qualitative

Specificity: 97.10%

Sensitivity: 88.90%

Application Details

Sample Volume: 5 μL

Assay Time: 1 - 2 h

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C

Expiry Date: 12-18 months

Target Details

Target: Helicobacter Pylori IgA (Hp IgA)

Target Type: Antibody

Background: Helicobacter pylori is a spiral bacterium cultured from human gastric mucosa by Marshall in 1982. Studies have indicated that the presence of H. pylori is associated with a variety of gastrointestinal diseases including gastritis, duodenal and gastric ulcer, non-ulcer dyspepsia, gastric adenocarcinoma and lymphoma. The organism is present in 95-98% of patients with duodenal ulcer and 60-90% of patients with gastric ulcers. The studies have also demonstrated that removal of the organism by antimicrobial therapy is correlated with the resolution of symptoms and cure of diseases. Patients who present with clinical symptoms relating to the gastrointestinal tract can be diagnosed for H. pylori infection by two methods: 1) invasive techniques include biopsy followed by culture or histologic examination of biopsy specimen or direct detection of urease activity. 2) non-invasive techniques include urea breath tests, serological methods and stool antigen test. All of the testing performed on biopsy samples are subject to errors related to sampling and interference of contaminated bacteria. H. pylori IgA, testing the presence of H. pylori specific IgA antibody is the technique of choice for serologic tests because of its accuracy and simplicity.