Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

LAMB2 Products

(Laminin, beta 2 (Laminin S) (LAMB2))
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 2. The beta 2 chain contains the 7 structural domains typical of beta chains of laminin, including the short alpha region. However, unlike beta 1 chain, beta 2 has a more restricted tissue distribution. It is enriched in the basement membrane of muscles at the neuromuscular junctions, kidney glomerulus and vascular smooth muscle. Transgenic mice in which the beta 2 chain gene was inactivated by homologous recombination, showed defects in the maturation of neuromuscular junctions and impairment of glomerular filtration. Alternative splicing involving a non consensus 5' splice site (gc) in the 5' UTR of this gene has been reported. It was suggested that inefficient splicing of this first intron, which does not change the protein sequence, results in a greater abundance of the unspliced form of the transcript than the spliced form. The full-length nature of the spliced transcript is not known. [provided by RefSeq, Aug 2011].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured LAMB2 Categories

LAMB2 Antibodies

High quality antibodies with extensive validation data.

LAMB2 ELISA Kits

Reliable ELISA kits for a wide range of species.

LAMB2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LAMB2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7438904
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7444094
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7437305
Quantity 100 μL
Datasheet Datasheet

Recommended LAMB2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957390
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN454167
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN454168
Quantity 96 tests
Datasheet Datasheet

Recommended LAMB2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7404077
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401872
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395851
Quantity 100 μg
Datasheet Datasheet

Synonyms and alternative names related to LAMB2

laminin subunit beta 2 (LAMB2), laminin, beta 2 (Lamb2), laminin subunit beta 2 (Lamb2), laminin subunit beta 2 L homeolog (lamb2.L), laminin, beta 2 (laminin S) (LAMB2), AW211941, Lamb-2, lamb1, LAMC1, laminin, LAMS, Lams, lams, NPHS5, SLAM

Protein level used designations for LAMB2

  • S-LAM beta
  • S-laminin subunit beta
  • laminin B1s chain
  • laminin S
  • laminin subunit beta-2
  • Laminin S
  • laminin-11 subunit beta
  • laminin-14 subunit beta
  • laminin-15 subunit beta
  • laminin-3 subunit beta
  • laminin-4 subunit beta
  • laminin-7 subunit beta
  • laminin-9 subunit beta
  • laminin chain B3
  • laminin chain beta 2
  • laminin beta 2
  • laminin, beta 1
  • gamma 1 (formerly LAMB2)
  • laminin, gamma 1 (formerly LAMB2)
You are here:
Support