LOXL1 Products
(Lysyl Oxidase-Like 1 (LOXL1))
Categories
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008].
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Featured LOXL1 Categories
LOXL1 Antibodies
High quality antibodies with extensive validation data.
LOXL1 ELISA Kits
Reliable ELISA kits for a wide range of species.
LOXL1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LOXL1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7436069
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
- (2)
Cat. No.
ABIN517560
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, IF
Validations
- (3)
Cat. No.
ABIN948090
Quantity
100 μL
Datasheet
Datasheet
Recommended LOXL1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6957602
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957603
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5593939
Quantity
96 tests
Datasheet
Datasheet
Recommended LOXL1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3083187
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3121274
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7400942
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LOXL1 products
: "Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis." in: Disease models & mechanisms, Vol. 10, Issue 11, pp. 1301-1312, (2018) (PubMed).: "Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation." in: Current eye research, Vol. 41, Issue 10, pp. 1331-1338, (2016) (PubMed).
: "A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. ..." in: Nature genetics, Vol. 47, Issue 4, pp. 387-92, (2015) (PubMed).
: "High glucose induced differential expression of lysyl oxidase and its isoform in ARPE-19 cells." in: Current eye research, Vol. 38, Issue 1, pp. 194-203, (2013) (PubMed).
: "Gremlin utilizes canonical and non-canonical TGF? signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells." in: Experimental eye research, Vol. 113, pp. 117-27, (2013) (PubMed).
: "LOXL1 deficiency in the lamina cribrosa as candidate susceptibility factor for a pseudoexfoliation-specific risk of glaucoma." in: Ophthalmology, Vol. 119, Issue 9, pp. 1832-43, (2012) (PubMed).
: "Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 35, Issue 11, pp. 1063-8, (2012) (PubMed).
: "Transforming growth factor-beta induces extracellular matrix protein cross-linking lysyl oxidase (LOX) genes in human trabecular meshwork cells." in: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5240-50, (2011) (PubMed).
: "Diverse biological functions of extracellular collagen processing enzymes." in: Journal of cellular biochemistry, Vol. 96, Issue 5, pp. 927-37, (2005) (PubMed).
: "Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues." in: The American journal of pathology, Vol. 167, Issue 4, pp. 927-36, (2005) (PubMed).
Synonyms and alternative names related to LOXL1
lysyl oxidase like 1 (LOXL1), lysyl oxidase like 1 (loxl1), lysyl oxidase-like 1 (Loxl1), lysyl oxidase-like 1 (loxl1), lysyl oxidase like 1 L homeolog (loxl1.L), LOL, lol, LOXL, Loxl, loxl, loxl-1, oxl-1, si:ch211-238c15.1Protein level used designations for LOXL1
- lysyl oxidase-like 1
- lysyl oxidase homolog 1-like
- lysyl oxidase homolog 1
- lysyl oxidase-like protein 1
- lysyl oxidase 2
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