MAGE-Like 2 Products
(MAGE-Like 2 (MAGEL2))
Categories
Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. [provided by RefSeq, Oct 2010].
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Featured MAGE-Like 2 Categories
MAGE-Like 2 Antibodies
High quality antibodies with extensive validation data.
MAGE-Like 2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAGE-Like 2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC (p)
Validations
- (2)
- (2)
Cat. No.
ABIN545685
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN390122
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN7191360
Quantity
100 μL
Datasheet
Datasheet
Recommended MAGE-Like 2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3093669
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3137400
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our MAGE-Like 2 products
: "The human MAGEL2 gene and its mouse homologue are paternally expressed and mapped to the Prader-Willi region." in: Human molecular genetics, Vol. 8, Issue 13, pp. 2497-505, (2000) (PubMed).: "Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype." in: Human molecular genetics, Vol. 9, Issue 12, pp. 1813-9, (2000) (PubMed).
Synonyms and alternative names related to MAGE-Like 2
MAGE family member L2 (MAGEL2), melanoma antigen, family L, 2 (Magel2), MAGE family member L2 (Magel2), Mage-l2, MAGEL2, NDNL1, nM15, ns7Protein level used designations for MAGE-Like 2
- MAGE-like protein 2
- necdin-like protein 1
- protein nM15
- MAGE-like 2
- melanoma antigen-like gene 2
- necdin-like 1
- protein nS7
- melanoma antigen, family L, 2
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