MARK1 Proteins

(MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) (By similarity).

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6 results

MARK1 Protein (AA 1-795) (His tag)

custom-made MARK1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Mark1 Protein, UniprotID Q8VHJ5

3 images

Catalog No. ABIN7564762

Details

MARK1 Protein (AA 1-795) (His tag)

custom-made MARK1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant MARK1 Protein, UniprotID Q9P0L2

3 images

Catalog No. ABIN7554489

Details

MARK1 Protein (GST tag)

MARK1 Origin: Human Host: Insect Cells Recombinant 70 % - 90 % Func Active

Catalog No. ABIN5508998

Details

MARK1 Protein (AA 1-795) (Strep Tag)

custom-made MARK1 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3136746

Details

MARK1 Protein (AA 1-795) (Strep Tag)

custom-made MARK1 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3093697