Microtubule Star antibody (N-Term)
This anti-Microtubule Star antibody is a Rabbit Polyclonal antibody detecting Microtubule Star in IHC (p) and WB. Suitable for Human, Mouse and Rat.
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Catalog No. ABIN3031776
Quick Overview for Microtubule Star antibody (N-Term) (ABIN3031776)
Target
See all Microtubule Star (MTS) products
Microtubule Star (MTS)
Reactivity
Human, Mouse, Rat
Host
Rabbit
Clonality
Polyclonal
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Binding Specificity
- N-Term
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Purification
- Antigen affinity
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Immunogen
- An amino acid sequence from the N-terminus of human PPP2CA (FTKELDQWIEQLNEC) was used as the immunogen for this PP2Ac antibody (100% homologous in human, mouse and rat).
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Isotype
- IgG
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Application Notes
- Variations in secondary/substrate sensitivities and test protocols may require the PP2Ac antibody to be titrated for optimal performance.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- -20 °C
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Storage Comment
- The lyophilized PP2Ac antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
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- Microtubule Star (MTS)
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Alternative Name
- PP2Ac
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Background
- The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of PPP2CA is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
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UniProt
- P67775
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Pathways
- PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
Target
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