Microtubule Star antibody (N-Term)
Quick Overview for Microtubule Star antibody (N-Term) (ABIN3031776)
Target
See all Microtubule Star (MTS) productsReactivity
Host
Clonality
Application
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Binding Specificity
- N-Term
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Purpose
- PP2Ac Antibody (catalytic subunit) / PPP2CA
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Sequence
- FTKELDQWIE QLNEC
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Purification
- Antigen affinity
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Immunogen
- An amino acid sequence from the N-terminus of human PPP2CA (FTKELDQWIEQLNEC) was used as the immunogen for this PP2Ac antibody (100% homologous in human, mouse and rat).
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Isotype
- IgG
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Application Notes
- Variations in secondary/substrate sensitivities and test protocols may require the PP2Ac antibody to be titrated for optimal performance.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- The lyophilized PP2Ac antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freeze/thaws.
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- Microtubule Star (MTS)
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Alternative Name
- PP2Ac
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Background
- The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of PPP2CA is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
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UniProt
- P67775
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Pathways
- PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
Target
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