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MRPL12 Products

(Mitochondrial Ribosomal Protein L12 (MRPL12))

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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008].

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Featured MRPL12 Categories

MRPL12 Antibodies

High quality antibodies with extensive validation data.

MRPL12 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MRPL12 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), RNAi
Validations
  • (3)
  • (7)
Cat. No. ABIN562710
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN948420
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (2)
Cat. No. ABIN7074638
Quantity 100 μL
Datasheet Datasheet

Recommended MRPL12 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311289
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3087395
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3129510
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MRPL12 products

Richman, Davies, Shearwood, Ermer, Scott, Hibbs, Rackham, Filipovska: "A bifunctional protein regulates mitochondrial protein synthesis." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5483-94, (2014) (PubMed).

Chen, Cairns, Papandreou, Koong, Denko: "Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect." in: PLoS ONE, Vol. 4, Issue 9, pp. e7033, (2009) (PubMed).

Wang, Cotney, Shadel: "Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 12610-8, (2007) (PubMed).

Synonyms and alternative names related to MRPL12

mitochondrial ribosomal protein L12 (MRPL12), 39S ribosomal protein L12, mitochondrial (LOC409926), mitochondrial nucleoid protein (CAALFM_C207190CA), mitochondrial ribosomal protein L12 (Mrpl12), mitochondrial ribosomal protein L12 (mrpl12), mitochondrial ribosomal protein L12 L homeolog (mrpl12.L), 5c5-2, 0610034O11Rik, 1500031N16Rik, GB14723, im:6893415, L12mt, MRP-L12, MRP-L31/34, MRPL7, MRPL7/L12, MRPL12, mrpl12, Rpm12, RPML12, Rpml12, zgc:112445

Protein level used designations for MRPL12

  • 39S ribosomal protein L12, mitochondrial
  • MRP-L12
  • mitochondrial ribosomal protein L12
  • likely mitochondrial ribosomal protein (E. coli L7/L12)
  • L12mt
  • ribosomal protein, mitochondrial, L12
  • mitochondrial ribosomal protein L12 L homeolog
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