ARL11 Protein (AA 1-196) (His tag)
Quick Overview for ARL11 Protein (AA 1-196) (His tag) (ABIN667499)
Target
See all ARL11 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-196
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Purification tag / Conjugate
- This ARL11 protein is labelled with His tag.
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Sequence
- MGSVNSRGHK AEAQVVMMGL DSAGKTTLLY KLKGHQLVET LPTVGFNVEP LKAPGHVSLT LWDVGGQAPL RASWKDYLEG TDILVYVLDS TDEARLPESA AELTEVLNDP NMAGVPFLVL ANKQEAPDAL PLLKIRNRLS LERFQDHCWE LRGCSALTGE GLPEALQSLW SLLKSRSCMC LQARAHGAER GDSKRS
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Characteristics
- ARL11, 1-196aa, Human, His tag, E.coli
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Purification
- > 90% by SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 5 mM DTT, 30 % glycerol, 100 mM NaCl, 1 mM EDTA
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Handling Advice
- Avoid repeated freezing and thawing cycles
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- ARL11 (ADP-Ribosylation Factor-Like 11 (ARL11))
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Alternative Name
- ARLTS1/ARL11
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Background
- ARL11 (ADP-ribosylation factor-like protein 11), is a member of the ARF family of the Ras superfamily of small GTPases that are known to be involved in multiple regulatory pathways altered in human carcinogenesis. ARFs are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of choleratoxin. ARFs are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL11 is thought to function as a tumor suppressor that may play a role in the regulation of apoptosis. Recombinant human ARL11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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Molecular Weight
- 23.6 kDa (216aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_612459
Target
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