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NAPRT1 Products

(Nicotinate phosphoribosyltransferase (NAPRT))

Categories

Nicotinic acid (NA\; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT\; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008].

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Featured NAPRT1 Categories

NAPRT1 Antibodies

High quality antibodies with extensive validation data.

NAPRT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NAPRT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC, IF
Validations
  • (3)
Cat. No. ABIN6263515
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7246967
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN949786
Quantity 100 μL
Datasheet Datasheet

Recommended NAPRT1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231618
Quantity 96 tests
Datasheet Datasheet

Recommended NAPRT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311979
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2745752
Quantity 50 μg
Datasheet Datasheet
Reactivity Bacillus subtilis
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2745753
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our NAPRT1 products

Gaudino, Manfredonia, Managò, Audrito, Raffaelli, Vaisitti, Deaglio: "Subcellular Characterization of Nicotinamide Adenine Dinucleotide Biosynthesis in Metastatic Melanoma by Using Organelle-Specific Biosensors." in: Antioxidants & redox signaling, Vol. 31, Issue 15, pp. 1150-1165, (2019) (PubMed).

Managò, Audrito, Mazzola, Sorci, Gaudino, Gizzi, Vitale, Incarnato, Minazzato, Ianniello, Varriale, DAuria, Mengozzi, Politano, Oliviero, Raffaelli, Deaglio: "Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation." in: Nature communications, Vol. 10, Issue 1, pp. 4116, (2019) (PubMed).

Shames, Elkins, Walter, Holcomb, Du, Mohl, Xiao, Pham, Haverty, Liederer, Liang, Yauch, OBrien, Bourgon, Koeppen, Belmont: "Loss of NAPRT1 expression by tumor-specific promoter methylation provides a novel predictive biomarker for NAMPT inhibitors." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 24, pp. 6912-23, (2013) (PubMed).

Xiao, Elkins, Durieux, Lee, Oeh, Yang, Liang, DelNagro, Tremayne, Kwong, Liederer, Jackson, Belmont, Sampath, OBrien: "Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618." in: Neoplasia (New York, N.Y.), Vol. 15, Issue 10, pp. 1151-60, (2013) (PubMed).

Fagerberg, Stadler, Skogs, Hjelmare, Jonasson, Wiking, Abergh, Uhlén, Lundberg: "Mapping the subcellular protein distribution in three human cell lines." in: Journal of proteome research, Vol. 10, Issue 8, pp. 3766-77, (2011) (PubMed).

Synonyms and alternative names related to NAPRT1

nicotinate phosphoribosyltransferase (NAPRT), nicotinate phosphoribosyltransferase (Naprt), nicotinate phosphoribosyltransferase (naprt), 9130210N20Rik, PP3856, zgc:77870

Protein level used designations for NAPRT1

  • FHA-HIT-interacting protein
  • NAPRTase
  • nicotinate phosphoribosyltransferase
  • nicotinate phosphoribosyltransferase domain-containing protein 1
  • nicotinic acid phosphoribosyltransferase
  • nicotinate phosphoribosyltransferase-like protein
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