Browse our anti-Activin Receptor Type IC (ACVR1C) Antibodies

Full name:: anti-Activin Receptor Type IC Antibodies (ACVR1C)

On www.antibodies-online.com are 118 Activin Receptor Type IC (ACVR1C) Antibodies from 26 different suppliers available. Additionally we are shipping Activin Receptor Type IC Proteins (12) and Activin Receptor Type IC Kits (3) and many more products for this protein. A total of 147 Activin Receptor Type IC products are currently listed.

Synonyms:: ACVRLK7, Alk-7, Alk7, C230097P10, habrec1

list all antibodies	Gene Name	GeneID	UniProt
	ACVR1C	130399	Q8NER5
	ACVR1C	269275	Q8K348
	ACVR1C	245921	P70539
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Top referenced anti-Activin Receptor Type IC Antibodies

Mouse (Murine) Polyclonal ACVR1C Primary Antibody for WB - ABIN658527 : Andersson, Korach-Andre, Reissmann, Ibáñez, Bertolino: Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
Show all 5 Pubmed References
Human Polyclonal ACVR1C Primary Antibody for IHC (p), WB - ABIN391157 : Munir, Xu, Wu, Yang, Lala, Peng: Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells. in The Journal of biological chemistry 2004 (PubMed)
Show all 3 Pubmed References
Human Monoclonal ACVR1C Primary Antibody for FACS - ABIN4896938 : Tengroth, Arebro, Larsson, Bachert, Georén, Cardell: Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps. in Scientific reports 2018 (PubMed)
Human Monoclonal ACVR1C Primary Antibody for CyTOF, FACS - ABIN4899939 : Puvanenthiran, Essapen, Seddon, Modjtahedi et al.: Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of small molecule tyrosine kinase ... in International journal of oncology 2017 (PubMed)

More Antibodies against Activin Receptor Type IC Interaction Partners

Human Activin Receptor Type IC (ACVR1C) interaction partners

Loss of ALK7 expression are associated with invasion, metastasis of the pancreatic ductal adenocarcinoma.
Alk7 is expressed in male germ cells and Sertoli cells.
ACVR (show ACRV1 Antibodies) 1C is a tumor suppressor, and lowered ACVR (show ACRV1 Antibodies) 1C expression is an important marker for the metastasis, invasion, and prognosis of gallbladder cancer.
Our findings suggested that the ALK7 gene polymorphism rs13010956 was significantly associated with metabolic syndrome risk in females and may be involved in cardiovascular remodeling in metabolic syndrome patients.
reduction or lack of ALK7 expression may account for the loss of its ligand sensitivity of breast cancer cells, thereby leading to breast tumor progression.
These findings suggest that the Nodal/ALK7 pathway plays important roles in human placentation and that its abnormal signaling may contribute to the development of preeclampsia.
ALK7 and its isoforms are expressed in human placentae of different stages of pregnancy and that their expression is developmentally regulated
ALK7 induces apoptosis through activation of the traditional TGF-beta (show TGFB1 Antibodies) pathway components
the Nodal-ALK7 pathway inhibits cell proliferation by inducing G(1) cell cycle arrest
AB and activin B and is responsible for ac (show Actbeta Antibodies)tivin-mediated se (show Actbeta Antibodies)cretion of insulin from pancrea (show Actbeta Antibodies)tic beta cell line, MIN6.

Mouse (Murine) Activin Receptor Type IC (ACVR1C) interaction partners

Data, including data from studies using knockout mice, suggest that Gdf3 (show GDF3 Antibodies)-Alk7 axis between adipose tissue macrophages and adipocytes represents previously unrecognized mechanism by which insulin (show INS Antibodies) regulates both fat metabolism/lipolysis and adiposity. (Gdf3 (show GDF3 Antibodies) = growth differentiation factor-3 (show GDF3 Antibodies); Alk7 = activin receptor-like kinase-7)

Thus, the authors define a new memory mechanism by which learning reverses microRNA-mediated silencing of the novel plasticity protein ACVR1C via translin (show TSN Antibodies)/trax (show TSNAX Antibodies).

ALK7 protects against pathological cardiac hypertrophy in mice.

These findings suggest that endogenous expression of ALK7 is necessary to maintain repolarizing K+ currents in ventricular cardiomyocytes, and finally prevent action potential prolongation and ventricular arrhythmia.

ALK7 signaling contributes to diet-induced catecholamine resistance in adipose tissue; ALK7 inhibitors may have therapeutic value in human obesity.

Signaling through the TGF beta (show TGFB1 Antibodies)-activin (show Actbeta Antibodies) receptors ALK4 (show ACVR1B Antibodies)/5/7 regulates testis formation and male germ cell development.

Alk7 is involved in modulation of adipose tissue metabolism in response to beta3-adrenergic receptor (show ADRB3 Antibodies) activation.

Data indicate that activin receptor ALK7-knockout females showed delayed onset of puberty and abnormal estrous cyclicity.

Activin receptor-like kinase 7 suppresses lipolysis to accumulate fat in obesity through downregulation of peroxisome proliferator-activated receptor gamma (show PPARG Antibodies) and C/EBPalpha (show CEBPA Antibodies).

Knockdown or pharmacological inhibition of the Nodal/Activin receptor Alk4 (show ACVR1B Antibodies)/7 in cancer stem cells virtually abrogated their self-renewal capacity and in vivo tumorigenicity

Activin Receptor Type IC (ACVR1C) Antigen Profile

Antigen Summary

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001

Alternative names and synonyms associated with Activin Receptor Type IC (ACVR1C)

activin A receptor type 1C (ACVR1C) antibody

activin A receptor, type IC (Acvr1c) antibody

activin A receptor type 1C (Acvr1c) antibody

ACVRLK7 antibody

Alk-7 antibody

Alk7 antibody

C230097P10 antibody

habrec1 antibody

Protein level used designations for ACVR1C

ACTR-IC , ALK-7 , activin receptor type IC , activin receptor type-1C , activin receptor-like kinase 7 , TGF-beta type 1 receptor , activin A receptor, type IC

GENE ID SPECIES

130399 Homo sapiens

269275 Mus musculus

245921 Rattus norvegicus

488361 Canis lupus familiaris

100156756 Sus scrofa

536380 Bos taurus

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anti-Activity-Regulated Cytoskeleton-Associated Protein Antibodies

anti-Acyl-CoA Binding Domain Containing 3 Antibodies

anti-Acyl-CoA Binding Domain Containing 4 Antibodies

anti-Acyl-CoA Binding Domain Containing 5 Antibodies

anti-Acyl-CoA Binding Domain Containing 6 Antibodies

anti-Acyl-CoA Binding Domain Containing 7 Antibodies

anti-Acyl-CoA Dehydrogenase Family, Member 10 Antibodies

anti-Acyl-CoA Dehydrogenase Family, Member 11 Antibodies

anti-Acyl-CoA Dehydrogenase Family, Member 8 Antibodies

anti-Acyl-CoA Dehydrogenase Family, Member 9 Antibodies

anti-Acyl-CoA Dehydrogenase, C-2 To C-3 Short Chain Antibodies

anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain Antibodies

anti-Acyl-CoA Dehydrogenase, Long Chain Antibodies

anti-Acyl-CoA Dehydrogenase, Short/branched Chain Antibodies

anti-Acyl-CoA Dehydrogenase, Very Long Chain Antibodies

anti-Acyl-CoA Oxidase 1, Palmitoyl Antibodies

anti-Acyl-CoA Oxidase 2, Branched Chain Antibodies

anti-Acyl-CoA Oxidase 3, Pristanoyl Antibodies

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GENE ID	SPECIES
130399	Homo sapiens
269275	Mus musculus
245921	Rattus norvegicus
488361	Canis lupus familiaris
100156756	Sus scrofa
536380	Bos taurus

Show all anti-Activin Receptor Type IC (ACVR1C) Antibodies with Pubmed References

Human Activin Receptor Type IC (ACVR1C) interaction partners

Mouse (Murine) Activin Receptor Type IC (ACVR1C) interaction partners

Antigen Summary

Alternative names and synonyms associated with Activin Receptor Type IC (ACVR1C)

Protein level used designations for ACVR1C