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NFKB2 ELISA Kits

(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF- kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. In a non-canonical activation pathway, the MAP3K14- activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. The NF-kappa-B heterodimeric RelB-p52 complex is a transcriptional activator. The NF-kappa-B p52-p52 homodimer is a transcriptional repressor. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function. p52 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. p52 and p100 are respectively the minor and major form\; the processing of p100 being relatively poor. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65 (By similarity).
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kit Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kit Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kit (ABIN6968989)

NFKB2 Reactivity: Mouse Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate

Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kit Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kit Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kit (ABIN6968988)

NFKB2 Reactivity: Human Colorimetric Sandwich ELISA 0.313 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate

Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kit Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kit Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) ELISA Kit (ABIN6958240)

NFKB2 Reactivity: Human Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Tissue Homogenate

NFKB2 ELISA Kits by Reactivity

Find NFKB2 ELISA Kits for a variety of species such as anti-Human NFKB2, anti-Mouse NFKB2, anti-Rat NFKB2. The species listed below are among those available. Click on a link to go to the corresponding products.

NFKB2 ELISA Kits by Detection Method

Find NFKB2 ELISA Kits with a specific Detection Method. The Detection Method listed below are among those available. Click on a link to go to the corresponding products.

NFKB2 ELISA Kits by Analytical Method

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NFKB2 ELISA Kits by Method Type

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NFKB2 ELISA Kits by Sample

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NFKB2 ELISA Kits by Binding Specificity

Find NFKB2 ELISA Kits with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Popular NFKB2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958241
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380470
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380651
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380652
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951668
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN2685065
Quantity 1 kit
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1145396
Quantity 96 tests
Datasheet Datasheet

Aliases for NFKB2 ELISA Kits

nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 (Nfkb2) ELISA Kits
lyt ELISA Kits
NF-kappaB2 ELISA Kits
p49 ELISA Kits
p49/p100 ELISA Kits
p50B ELISA Kits
p52 ELISA Kits
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