NKX6-1 Products
(NK6 Homeobox 1 (NKX6-1))
Categories
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008].
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Featured NKX6-1 Categories
NKX6-1 Antibodies
High quality antibodies with extensive validation data.
NKX6-1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NKX6-1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NKX6-1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, StM
Validations
- (4)
Cat. No.
ABIN6940213
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (2)
Cat. No.
ABIN7436357
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, ICC, IF
Validations
- (2)
Cat. No.
ABIN6263651
Quantity
100 μL
Datasheet
Datasheet
Recommended NKX6-1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958207
Quantity
96 tests
Datasheet
Datasheet
Recommended NKX6-1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3084441
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3128039
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7399076
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NKX6-1 products
: "Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 2, pp. 191-211, (2019) (PubMed).: "B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib." in: JCI insight, Vol. 5, (2019) (PubMed).
: "Point mutations in the PDX1 transactivation domain impair human β-cell development and function." in: Molecular metabolism, Vol. 24, pp. 80-97, (2019) (PubMed).
: "The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function." in: Diabetes, (2019) (PubMed).
: "The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation." in: Frontiers in endocrinology, Vol. 10, pp. 293, (2019) (PubMed).
: "Generation of a human induced pluripotent stem cell line (HMGUi002-A) from a healthy male individual." in: Stem cell research, Vol. 39, pp. 101531, (2019) (PubMed).
: "Comprehensive genomic analysis identifies pathogenic variants in maturity-onset diabetes of the young (MODY) patients in South India. ..." in: BMC medical genetics, Vol. 19, Issue 1, pp. 22, (2018) (PubMed).
: "Defining a Novel Role for the PDX1 Transcription Factor in Islet β Cell Maturation and Proliferation During Weaning." in: Diabetes, (2017) (PubMed).
: "Identification of proliferative and mature β-cells in the islets of Langerhans. ..." in: Nature, Vol. 535, Issue 7612, pp. 430-4, (2016) (PubMed).
: "Cholestenoic acids regulate motor neuron survival via liver X receptors. ..." in: The Journal of clinical investigation, Vol. 124, Issue 11, pp. 4829-42, (2014) (PubMed).
Synonyms and alternative names related to NKX6-1
NK6 homeobox 1 (nkx6-1), NK6 homeobox 1 (NKX6-1), NK6 homeobox 1 (nkx6.1), NK6 homeobox 1 L homeolog (nkx6-1.L), NK6 homeobox 1 (Nkx6-1), nkx6.1, NKX6.1, Nkx6.1, nkx6a, NKX6A, Nkx6a, Nkx61, zgc:92879Protein level used designations for NKX6-1
- NK6 transcription factor related, locus 1
- NK6 homeobox 1
- NK homeo box, family 6, member A
- NK homeobox, family 6, A
- NK6 transcription factor homolog A
- homeobox protein NK-6 homolog A
- homeobox protein Nkx-6.1
- NK6 transcription factor related locus 1
- Drosophila NK transcription factor related, gene family 6, locus 1
- homeodomain transcription factor Nkx6.1
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