E3 SUMO-Protein Ligase NSE2 Proteins
(E3 SUMO-Protein Ligase NSE2 (NSMCE2))
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).
| Catalog no. | Product | Reactivity | Host / Clonality | Application | Price & lead time |
|---|---|---|---|---|---|
| NSMCE2 Protein (AA 1-247) (His tag) | Human | HEK-293 Cells |
|
starts at $12,595.45
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|
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| NSMCE2 Protein (AA 1-247) (His tag) | Mouse | HEK-293 Cells |
|
starts at $12,595.45
View price
|
|
| NSMCE2 Protein (AA 1-247) (GST tag) | Human | Wheat germ |
|
$475.39
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|
|
| NSMCE2 Protein (AA 1-310) (His tag) | Human | Escherichia coli (E. coli) |
|
$584.62
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|
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| NSMCE2 Protein | Human | Escherichia coli (E. coli) |
|
$823.89
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|
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| NSMCE2 Protein (AA 1-247) (Strep Tag) | Human | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
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|
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| NSMCE2 Protein (AA 1-247) (Strep Tag) | Mouse | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
View price
|
|
| NSMCE2 Protein (AA 11-309) (His tag) | Human | Escherichia coli (E. coli) |
|
$1,567.28
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|
|
| NSMCE2 Protein (Myc-DYKDDDDK Tag) | Human | HEK-293 Cells |
|
$1,112.40
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|
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| NSMCE2 Protein (His tag) | Human | Escherichia coli (E. coli) |
|
$396.00
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|
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| NSMCE2 Protein (AA 1-250) (His tag) | Schizosaccharomyces pombe | Yeast |
|
$2,826.76
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|
|
| NSMCE2 Protein (AA 1-238) (His tag) | Xenopus laevis | Yeast |
|
$2,785.56
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|
|
| NSMCE2 Protein (AA 1-248) (His tag) | Cow | Yeast |
|
$1,279.00
View price
|
|
| NSMCE2 Protein (AA 1-247) (His tag) | Rat | Yeast |
|
$1,279.00
View price
|
Protein
- PS (Protein Structure: Validation image available)
- Grade
- custom-made
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7554766
starts at
$12,595.45
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to:
United States
Delivery in 41 to 67 Business Days
Protein
- PS (Protein Structure: Validation image available)
- Grade
- custom-made
- Origin
- Mouse
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7564788
starts at
$12,595.45
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to:
United States
Delivery in 41 to 67 Business Days
Protein
- AP (Affinity Purification: Listed application)
- AA (Antibody Array: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Origin
- Human
- Host
- Wheat germ
- Protein Type
- Recombinant
Catalog No. ABIN1313078
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 14 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- > 85 %
Catalog No. ABIN5853389
$584.62
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 18 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- > 85 % pure
Catalog No. ABIN2129182
$823.89
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 9 to 12 Business Days
Protein
- ELISA (ELISA: Listed application)
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Grade
- custom-made
- Origin
- Human
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3094191
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
0.5 mg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- ELISA (ELISA: Listed application)
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Grade
- custom-made
- Origin
- Mouse
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3136789
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
0.5 mg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
Catalog No. ABIN7888758
$1,567.28
Plus shipping costs $50.00, if applicable $20.00 dry ice
500 μg
Shipping to:
United States
Delivery in 11 to 22 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2720825
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2727651
$396.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Protein
- ELISA (ELISA: Listed application)
- Origin
- Schizosaccharomyces pombe
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN1630605
$2,826.76
Plus shipping costs $50.00
1 mg
Shipping to:
United States
Delivery in 60 to 72 Business Days
Protein
- ELISA (ELISA: Listed application)
- Origin
- Xenopus laevis
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN1678295
$2,785.56
Plus shipping costs $50.00
1 mg
Shipping to:
United States
Delivery in 60 to 72 Business Days
Protein
- ELISA (ELISA: Listed application)
- Origin
- Cow
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN7588767
$1,279.00
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 60 to 72 Business Days
Protein
- ELISA (ELISA: Listed application)
- Origin
- Rat
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN7589951
$1,279.00
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 60 to 72 Business Days
Aliases for E3 SUMO-Protein Ligase NSE2 Proteins
family with sequence similarity 84 member B (FAM84B) ProteinsNSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2) Proteins
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2) Proteins
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L) Proteins
Smc5-6 complex non-SMC subunit 2 (nse2) Proteins
family with sequence similarity 84, member B (Fam84b) Proteins
family with sequence similarity 84, member B (fam84b) Proteins
1110014D18Rik Proteins
AI661537 Proteins
BCMP101 Proteins
BF642811 Proteins
C8orf36 Proteins
D330050I23Rik Proteins
MMS21 Proteins
Non-SMC element 2 Proteins
NSE2 Proteins
RGD1305156 Proteins
si:dkey-5e12.3 Proteins
zgc:153371 Proteins
ZMIZ7 Proteins
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