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Osteopontin Proteins

(Secreted phosphoprotein 1 (SPP1))
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

56 results

SPP1 Origin: Rat Host: HEK-293 Cells Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7665372
-15% Promotion 2026
$575.13
$676.62
save $101.49 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
 
SPP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, AcA Active
Catalog No. ABIN7677240
-15% Promotion 2026
$487.12
$573.08
save $85.96 (-15 %)
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SPP1 Origin: Cow Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7411462
-15% Promotion 2026
$545.39
$641.63
save $96.24 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SPP1 Origin: Rabbit Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Catalog No. ABIN7392695
-15% Promotion 2026
$627.11
$737.78
save $110.67 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SPP1 Origin: Pig Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7392689
-15% Promotion 2026
$627.11
$737.78
save $110.67 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SPP1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7392686
-15% Promotion 2026
$640.73
$753.80
save $113.07 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SPP1 Origin: Human Host: HEK-293T Cells Recombinant > 97 % pure Active
Catalog No. ABIN935702
-15% Promotion 2026
$867.14
$1,020.17
save $153.03 (-15 %)
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 16 to 21 Business Days
 
SPP1 Origin: Dog Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7422292
-15% Promotion 2026
$681.60
$801.88
save $120.28 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SPP1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Catalog No. ABIN7392692
-15% Promotion 2026
$681.60
$801.88
save $120.28 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SPP1 Origin: Rhesus Monkey Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7414807
-15% Promotion 2026
$695.21
$817.90
save $122.69 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SPP1 Origin: Dog Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7392683
-15% Promotion 2026
$749.70
$882.00
save $132.30 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SPP1 Origin: Mouse Host: Mammalian Cells Recombinant > 90 % Inactive
Catalog No. ABIN7669716
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
SPP1 Origin: Human Host: Escherichia coli (E. coli) Native > 95 % pure ELISA, LETIA
Catalog No. ABIN2130961
-15% Promotion 2026
$3,069.74
$3,611.46
save $541.72 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 9 to 11 Business Days
 
SPP1 Origin: Human Host: Human Native
Catalog No. ABIN1684543
-15% Promotion 2026
$2,267.19
$2,667.28
save $400.09 (-15 %)
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 3 to 4 Business Days
 
SPP1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728021
$300.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to: United States
Delivery in 4 to 8 Business Days
 
SPP1 Origin: Mouse Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5713862
$633.60
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 11 Business Days
 
SPP1 Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728020
$720.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Will be delivered in 11 Business Days
 
SPP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728019
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Will be delivered in 11 Business Days
 
SPP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728018
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Will be delivered in 11 Business Days
 
SPP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728017
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Will be delivered in 11 Business Days
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Antibody Production (AbP)
    • Standard (STD)
    • Activity Assay (AcA)
    • Cell Culture (CC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Latex enhanced turbidimetric Immunoassay (LETIA)
    • Protein Interaction (PI)
  • Reactivity
    • Human
    • Mouse
    • Cow
    • Pig
    • Rat
    • Rabbit
    • Dog
    • Chicken
    • Cynomolgus
    • Rhesus Monkey
    • Sheep
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • Mammalian Cells
    • Bacteria
    • HEK-293T Cells
    • Human
    • Human Cells
    • Insect cells (Sf9)
    • Wheat germ
  • Binding Specificity
    • AA 17-294
    • AA 17-300
    • AA 17-278
    • AA 17-314
    • AA 17-317
    • Transcript Variant 2
    • AA 17-287
    • AA 17-303
    • partial
    • AA 1-272
    • AA 1-300
    • AA 138-294
    • AA 17-264
    • AA 17-277
    • AA 17-290
    • AA 17-311
    • AA 18-314
    • AA 2-56
    • AA 28-61
    • AA 37-303
    • AA 650-920
    • AA 7-232
    • E99G
    • Transcript Variant 1
    • Transcript Variant 3
  • Conjugate
    • His tag
    • Un-conjugated
    • Myc-DYKDDDDK Tag
    • His tag,GST tag
    • His-Avi Tag,Biotin
    • His-IF2DI Tag
    • DYKDDDDK Tag
    • GST tag
    • His tag,SUMO Tag
    • His-SUMO Tag
  • Protein Type
    • Recombinant
    • Native
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • CUSABIO
    • OriGene
    • Abbexa
    • ACROBiosystems
    • Cloud-Clone
    • Biospes
    • ITSI-Biosciences
    • ProteoGenix
    • Signalway

Latest Publications for our Osteopontin Proteins

Shiraga, Min, VanDusen, Clayman, Miner, Terrell, Sherbotie, Foreman, Przysiecki, Neilson: "Inhibition of calcium oxalate crystal growth in vitro by uropontin: another member of the aspartic acid-rich protein superfamily." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 1, pp. 426-30, (1992) (PubMed).

Young, Kerr, Termine, Wewer, Wang, McBride, Fisher: "cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)." in: Genomics, Vol. 7, Issue 4, pp. 491-502, (1990) (PubMed).

Kiefer, Bauer, Barr: "The cDNA and derived amino acid sequence for human osteopontin." in: Nucleic acids research, Vol. 17, Issue 8, pp. 3306, (1989) (PubMed).

Aliases for Osteopontin Proteins

secreted phosphoprotein 1 (SPP1) Proteins
secreted phosphoprotein 1 (Spp1) Proteins
secreted phosphoprotein 1 (spp1) Proteins
2AR Proteins
Apl-1 Proteins
BNSP Proteins
Bsp Proteins
BSPI Proteins
Eta Proteins
ETA-1 Proteins
OP Proteins
OPN Proteins
Opn Proteins
Opnl Proteins
OSP Proteins
Ric Proteins
Spp-1 Proteins
zgc:111821 Proteins
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