Osteopontin Proteins
(Secreted phosphoprotein 1 (SPP1))
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
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51 results
MALS verified
SPP1
Origin: Mouse
Host: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
SPP1
Origin: Human
Host: HEK-293 Cells
Recombinant
>80 % as determined by SDS-PAGE.
Latest Publications for our Osteopontin Proteins
: "Inhibition of calcium oxalate crystal growth in vitro by uropontin: another member of the aspartic acid-rich protein superfamily." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 1, pp. 426-30, (1992) (PubMed).: "cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)." in: Genomics, Vol. 7, Issue 4, pp. 491-502, (1990) (PubMed).
: "The cDNA and derived amino acid sequence for human osteopontin." in: Nucleic acids research, Vol. 17, Issue 8, pp. 3306, (1989) (PubMed).
Aliases for Osteopontin Proteins
secreted phosphoprotein 1 (SPP1) Proteinssecreted phosphoprotein 1 (Spp1) Proteins
secreted phosphoprotein 1 (spp1) Proteins
2AR Proteins
Apl-1 Proteins
BNSP Proteins
Bsp Proteins
BSPI Proteins
Eta Proteins
ETA-1 Proteins
OP Proteins
OPN Proteins
Opn Proteins
Opnl Proteins
OSP Proteins
Ric Proteins
Spp-1 Proteins
zgc:111821 Proteins
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