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anti-Rat (Rattus) TNFRSF10B Antibodies:
anti-Human TNFRSF10B Antibodies:
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Human Polyclonal TNFRSF10B Primary Antibody for FACS, ICC - ABIN4361766
Basile, Zacny, Münger et al.: The cytokines tumor necrosis factor-alpha (TNF-alpha ) and TNF-related apoptosis-inducing ligand differentially modulate proliferation and apoptotic pathways in human keratinocytes expressing the ... in The Journal of biological chemistry 2001
Show all 37 Pubmed References
Human Polyclonal TNFRSF10B Primary Antibody for FACS, ICC - ABIN4361767
Cuello, Ettenberg, Clark, Keane, Posner, Nau, Dennis, Lipkowitz et al.: Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that ... in Cancer research 2001
Show all 18 Pubmed References
Human Monoclonal TNFRSF10B Primary Antibody for CyTOF, FACS - ABIN4900599
Barbarotto, Corallini, Rimondi, Fadda, Mischiati, Grill, Vaccarezza, Celeghini: Differential effects of chemotherapeutic drugs versus the MDM-2 antagonist nutlin-3 on cell cycle progression and induction of apoptosis in SKW6.4 lymphoblastoid B-cells. in Journal of cellular biochemistry 2008
Show all 16 Pubmed References
Human Monoclonal TNFRSF10B Primary Antibody for FACS - ABIN4898056
Gupta, Francis, Nair, Mo, Aggarwal et al.: Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 ... in The Journal of biological chemistry 2013
Show all 13 Pubmed References
Human Monoclonal TNFRSF10B Primary Antibody for FACS - ABIN4898055
Peppa, Gill, Reynolds, Easom, Pallett, Schurich, Micco, Nebbia, Singh, Adams, Kennedy, Maini: Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion. in The Journal of experimental medicine 2013
Show all 13 Pubmed References
Human Monoclonal TNFRSF10B Primary Antibody for FACS, Func - ABIN1169245
Sprick, Rieser, Stahl, Grosse-Wilde, Weigand, Walczak: Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8. in The EMBO journal 2002
Show all 6 Pubmed References
Human Monoclonal TNFRSF10B Primary Antibody for - ABIN1383912
Sato, Niessner, Kopecky, Frye, Goronzy, Weyand: TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. in The Journal of experimental medicine 2006
Show all 3 Pubmed References
Mouse (Murine) Polyclonal TNFRSF10B Primary Antibody for CyTOF, FACS - ABIN4900408
Park, Wu, Choi, Najafi, Emami, Safa: P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5. in Biochemical pharmacology 2006
Show all 3 Pubmed References
Human Monoclonal TNFRSF10B Primary Antibody for FACS - ABIN1383914
Mérino, Lalaoui, Morizot, Schneider, Solary, Micheau: Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. in Molecular and cellular biology 2006
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Human Monoclonal TNFRSF10B Primary Antibody for IP - ABIN1383915
Vermot-Desroches, Sergent, Bonnin, Wijdenes: Characterization of monoclonal antibodies directed against trail or trail receptors. in Cellular immunology 2005
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our results demonstrated that nanovectorization of TRAIL with BNNTs enhanced its binding to both DR4 (show HLADRB4 Antibodies) and DR5 receptors at 37 degrees C. Our novel nanovector could potentially be used for delivering TRAIL to cells for cancer treatment
Both S1P (show MBTPS1 Antibodies) and caspase-8 (show CASP8 Antibodies) are critical for TRAF2 (show TRAF2 Antibodies) stabilization, polyubiquitination, subsequent activation of JNK (show MAPK8 Antibodies)/AP1 (show FOSB Antibodies) signaling and MMP1 (show MMP1 Antibodies) expression and final promotion of cell invasion.
DNA fragmentation, mitochondrial membrane potential and western blot analyses showed that MIC inhibited the growth of these cells by both mitochondrialmediated and death receptor (DR5)mediated apoptosis pathways
targeting of lysosomes by chloroquine deregulates DR5 trafficking and abrogates 5-FU- but not TRAIL-stimulated cell elimination, hence suggesting a novel mechanism for receptor activation
siRNA silencing of CHOP (show DDIT3 Antibodies) significantly reduced cyproterone acetate-induced DR5 up-regulation and TRAIL sensitivity in prostate cancer cells. Our study shows a novel effect of cyproterone acetate on apoptosis pathways in prostate cancer cells and raises the possibility that a combination of TRAIL with cyproterone acetate could be a promising strategy for treating castration-resistant prostate cancer
PU.1 supports TRAIL-induced cell death by inhibiting RelA (show NFkBP65 Antibodies)-mediated cell survival and inducing DR5 expression.
The results demonstrated CaM binding to DR5-mediated DISC in a calcium dependent manner and may identify CaM as a key regulator of DR5-mediated DISC formation for apoptosis in breast cancer.
The oncogene (show RAB1A Antibodies)-like extracellular miR (show MLXIP Antibodies)-1246 could act as a signaling messenger between irradiated and non-irradiated lung cancer cells, more importantly, it contributes to cell radioresistance by directly suppressing the DR5 gene.
These results reveal KDM4A (show KDM4A Antibodies) as a key epigenetic silencer of TRAIL and DR5 in tumors.
Data show that 4EGI-1 compound induced apoptosis in nasopharyngeal carcinoma cells through the death receptor 5 (DR5) on 4E-BP1 (show EIF4EBP1 Antibodies) dephosphorylation exerting positive influence on their anti-tumor activities.
Death receptor5 pathway and mitochondrial pathway, which are likely mediated by HIF-1alpha (show HIF1A Antibodies), contribute to hypoxia-induced spermatocyte apoptosis.
Authors demonstrate, for the first time, expression of TNF-related apoptosis-inducing ligand (TRAIL (show TNFSF10 Antibodies)) and its signaling death receptor 5 (DR5) in the murine inner ear.
Malignant transformation in the endometrium is related to reduction of membrane DR4 (show HLADRB4 Antibodies) and DR5 expression.
TRAIL expression by osteoclast-like cells is increased in the presence of RANKL (show TNFSF11 Antibodies) and after scraping; DcR2 (show TNFRSF10D Antibodies) expression peaks at 24 hours, and and decreases at 5 days; DR5 expression peaks at 5 days
Induction of death receptor 5 expression in tumor vasculature by perifosine restores the vascular disruption activity of TRAIL-expressing CD34 (show CD34 Antibodies)(+) cells.
TRAIL-DR5 interaction promoted malignant behaviors of B16F10 cells.
results suggest that the transmembrane domains together with their adjacent stalk regions can play a major role in control of death receptor activation thereby contributing to cell type specific differences in TRAILR1 and TRAILR2 signaling
DR5 is selectively expressed by neuroprogenitor cells and newborn neurons.
Results suggest that excessive iodine could induce TRAIL and DR5 abnormal expression in thyroid. TRAIL band with DR5 to promote follicular cells apoptosis thus mediate thyroid destruction in EAT.
NK cells inhibit dendritic cell cross-priming, but not direct priming, in a TRAIL/DR5-dependent manner.
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
tumor necrosis factor receptor superfamily, member 10b
, death receptor-M2
, death receptor-M1
, Fas-like protein
, TNF-related apoptosis-inducing ligand receptor 2
, apoptosis inducing protein TRICK2A/2B
, apoptosis inducing receptor TRAIL-R2
, cytotoxic TRAIL receptor-2
, death domain containing receptor for TRAIL/Apo-2L
, death receptor 5
, p53-regulated DNA damage-inducible cell death receptor(killer)
, tumor necrosis factor receptor superfamily member 10B
, tumor necrosis factor receptor-like protein ZTNFR9
, KILLER/DR5 TRAIL death-inducing receptor