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PD-L1 Proteins

(CD274 (PD-L1))
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

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80 results

PD-L1 Protein (AA 34-241) (His tag)
PD-L1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % WB, SDS, Imm, PC
Catalog No. ABIN7411294
Details
Details
 
PD-L1 Protein (AA 34-241) (His tag,GST tag)
PD-L1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7416331
Details
Details
 
PD-L1 Protein
PD-L1 Origin: Human Host: Wheat germ Recombinant AP
Catalog No. ABIN1329970
Details
Details
 
PD-L1 Protein (Fc Tag,AVI tag)
PD-L1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319726
Details
Details
 
PD-L1 Protein (His tag)
PD-L1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7668351
Details
Details
 
PD-L1 Protein (AA 1-239) (His tag)
PD-L1 Origin: Human Host: Mammalian Cells Recombinant > 90 % Inactive
Catalog No. ABIN7668349
Details
Details
 
PD-L1 Protein (AA 1-239) (His tag)
PD-L1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % Inactive
Catalog No. ABIN7668348
Details
Details
 
PD-L1 Protein (AA 19-238) (SUMO Tag)
PD-L1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % Inactive
Catalog No. ABIN7668350
Details
Details
 
PD-L1 Protein (AA 19-238) (Fc Tag)
PD-L1 Origin: Dog Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN6992357
Details
Details
 
PD-L1 Protein (AA 19-238) (His tag)
PD-L1 Origin: Rabbit Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN6809862
Details
Details
 
PD-L1 Protein (AA 19-238) (Fc Tag)
PD-L1 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN2181631
Details
Details
 
PD-L1 Protein (DYKDDDDK Tag)
PD-L1 Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713592
Details
Details
 
PD-L1 Protein (DYKDDDDK-His Tag)
PD-L1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713589
Details
Details
 
PD-L1 Protein
PD-L1 Origin: Dog Host: Mammalian Cells 90 % Func
Catalog No. ABIN4948846
Details
Details
 
PD-L1 Protein (His tag)
MALS verified PD-L1 Origin: Dog Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7121291
Details
Details
 
PD-L1 Protein (partial) (Fc Tag)
PD-L1 Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. WB, ELISA Active
Catalog No. ABIN5608342
Details
Details
 
PD-L1 Protein (Twin-Strep tag)
PD-L1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
Catalog No. ABIN2566857
Details
Details
 
PD-L1 Protein (partial) (Fc Tag)
PD-L1 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
Catalog No. ABIN5608343
Details
Details
 
PD-L1 Protein (AA 19-239) (Fc Tag,AVI tag)
PD-L1 Origin: Human Host: Human Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. WB, SDS, ELISA, MS
Catalog No. ABIN7314190
Details
Details
 
PD-L1 Protein (His-Avi Tag,Biotin)
MALS verified PD-L1 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7199143
Details
Details
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Production (AbP)
    • Standard (STD)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Mass Spectrometry (MS)
    • Protein Interaction (PI)
  • Reactivity
    • Human
    • Mouse
    • Cynomolgus
    • Rhesus Monkey
    • Dog
    • Rat
    • Rabbit
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • HEK-293 Cells
    • Human Cells
    • Escherichia coli (E. coli)
    • Mammalian Cells
    • CHO Cells
    • Wheat germ
    • Baculovirus infected Insect Cells
    • HEK-293T Cells
    • Insect cells (Sf9)
  • Binding Specificity
    • AA 19-238
    • AA 19-239
    • AA 1-239
    • AA 18-238
    • AA 19-134
    • AA 19-237
    • AA 34-241
    • partial
    • AA 1-238
    • AA 128-238
    • AA 141-240
    • AA 19-132
    • AA 19-226
    • AA 24-234
    • AA 48-290
  • Conjugate
    • His tag
    • Fc Tag
    • Un-conjugated
    • DYKDDDDK Tag
    • mFc Tag
    • Fc Tag,AVI tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,His tag
    • His tag,AVI tag,Biotin
    • His tag,Biotin
    • His-Avi Tag,Biotin
    • DYKDDDDK-His Tag
    • Fc Tag,ECD
    • GST tag
    • His tag,Fc Tag,AVI tag,Biotin
    • His tag,GST tag
    • His-DYKDDDDK-Strep II Tag
    • His-IF2DI Tag
    • Llama Fc Tag
    • SUMO Tag
    • Strep Tag
    • Twin-Strep tag
    • hIgG-His-tag
    • mFc-His Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
    • Frozen
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • ProSci
    • OriGene
    • Cohesion Biosciences
    • ProteoGenix

Latest Publications for our PD-L1 Proteins

Ye, Yuan, Yue, Rubin, Chen: "Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model." in: Pharmaceutics, Vol. 13, Issue 2, (2021) (PubMed).

Li, Ren, Zhao, Lou: "PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging." in: The Analyst, Vol. 146, Issue 9, pp. 2910-2918, (2021) (PubMed).

Fan, Tian, Chen, Liu, Zhou, He, Coleman, Dong, Li, Huang, Xu, Zhang, Gao, Zhou, Ding, Chen: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." in: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).

Li, Course, McNeish, Drescher, Valdmanis, Lieber: "Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models." in: Cancer research, Vol. 80, Issue 3, pp. 549-560, (2020) (PubMed).

Lu, Xue, Deng, Zhou, Yu, Deng, Huang, Yi, Liang, Wang, Shen, Tong, Wang, Li, Song, Li, Su, Ding, Gong, Zhu, Wang, Zou, Zhang, Li, Zhou, Liu, Yu, Wang, Zhang, Yin, Xia, Zeng, Zhou, Ying, Chen, Wei, Li et al.: "Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer. ..." in: Nature medicine, Vol. 26, Issue 5, pp. 732-740, (2020) (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Tocheva, Lerrer, Mor: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).

Ganesan, Ahmed, Okoye, Arutyunova, Babu, Turnbull, Kundu, Shields, Agopsowicz, Xu, Tabana, Srivastava, Zhang, Moon, Belovodskiy, Hena, Kandadai, Hosseini, Hitt, Walker, Smylie, West, Siraki, Lemieux et al.: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).

Chen, Xu, Du, Hou, Fan, Wu, Yan: "Enhanced Expression of PD-L1 on Microglia After Surgical Brain Injury Exerts Self-Protection from Inflammation and Promotes Neurological Repair." in: Neurochemical research, Vol. 44, Issue 11, pp. 2470-2481, (2019) (PubMed).

Son, Park, Seo, Lee, Heo, Kim: "A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model." in: Journal of drug targeting, pp. 1-9, (2019) (PubMed).

Aliases for PD-L1 Proteins

CD274 molecule (CD274) Proteins
CD274 antigen (Cd274) Proteins
programmed cell death 1 ligand 2 (PDCD1LG2) Proteins
CD274 molecule (Cd274) Proteins
A530045L16Rik Proteins
B7-H Proteins
B7H1 Proteins
B7h1 Proteins
PD-L1 Proteins
PDCD1L1 Proteins
Pdcd1l1 Proteins
PDCD1LG1 Proteins
Pdcd1lg1 Proteins
PDL1 Proteins
Pdl1 Proteins
RGD1566211 Proteins

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