PDE12 Proteins
(Phosphodiesterase 12 (PDE12))
Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs) (By similarity).
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3 results
PDE12
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
PC, WB, Imm, SDS
PDE12
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aliases for PDE12 Proteins
phosphodiesterase 12 S homeolog (pde12.S) Proteinsphosphodiesterase 12 (PDE12) Proteins
phosphodiesterase 12 (pde12) Proteins
phosphodiesterase 12 (Pde12) Proteins
2'-PDE Proteins
E430028B21Rik Proteins
LRRGT00074 Proteins
RGD1310975 Proteins
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