CAMP Responsive Element Modulator (CREM) (C-Term) Peptide
CREM
Reactivity: Human, Rat
Host: Synthetic
BP, WB
-
- Target See all CREM products
- CREM (CAMP Responsive Element Modulator (CREM))
- Protein Region
- C-Term
- Origin
- Human, Rat
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Crem Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
CAMP Responsive Element Modulator (CREM) peptide
CREM Reactivity: Human, Rat, Cow, Mouse Host: Synthetic BP, Imm
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- CREM (CAMP Responsive Element Modulator (CREM))
- Synonyms
- CREM Peptide, ICER Peptide, CREM-2 Peptide, hCREM-2 Peptide, ICERI Peptide, Icer Peptide, cAMP responsive element modulator Peptide, CREM Peptide, Crem Peptide
- Background
-
Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.
Alias Symbols: Icer
Protein Size: 357 - Molecular Weight
- 39 kDa
- Gene ID
- 25620
- NCBI Accession
- NM_001110860, NP_001104330
- UniProt
- Q03061
-
You are here:
