Bleomycin Hydrolase (BLMH) (C-Term) Peptide
BLMH
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN1541188
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Bleomycin Hydrolase (BLMH) (C-Term) Peptide (ABIN1541188)
Target
BLMH
(Bleomycin Hydrolase (BLMH))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- GPITPLQFYK EHVKPLFNME DKICFVNDPR PQHKYNKLYT VDYLSNMVGG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Blmh Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BLMH (Bleomycin Hydrolase (BLMH))
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Background
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The encoded protein is a cytoplasmic cysteine peptidase involved in inactivation of bleomycin, a glycopeptide which is a component of combination chemotherapy regimens for cancer. This encoded enzyme is highly conserved, and it contains the signature active site residues of cysteine protease papain superfamily enzymes. It is postulated that this enzyme has protective effects against bleomycin-induced pulmonary fibrosis and bleomycin tumor resistance.
Alias Symbols: AI035728, Bh, Bmh
Protein Size: 455 -
Molecular Weight
- 50 kDa
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Gene ID
- 104184
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NCBI Accession
- NM_178645, NP_848760
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UniProt
- Q8R016
Target
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