Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (C-Term) Peptide
Quick Overview for Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (C-Term) Peptide (ABIN1541194)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- KMLHVDPQQR LTAVQVLKHP WIVNREYLSQ NQLSRQDVHL VKGAMAATYF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Rps6ka2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
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Background
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Rps6ka2 is a serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.
Alias Symbols: 90 kDa, D17Wsu134e, Rps6ka-rs1, Rsk3, p90rsk, pp90rsk
Protein Size: 733 -
Molecular Weight
- 81 kDa
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Gene ID
- 20112
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NCBI Accession
- NM_011299, NP_035429
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UniProt
- Q9WUT3
Target
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