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Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (C-Term) Peptide

RPS6KA2 Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN1541194

Quick Overview for Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (C-Term) Peptide (ABIN1541194)

Target

RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Origin

Human, Mouse

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    KMLHVDPQQR LTAVQVLKHP WIVNREYLSQ NQLSRQDVHL VKGAMAATYF

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-Rps6ka2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

    Background

    Rps6ka2 is a serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.

    Alias Symbols: 90 kDa, D17Wsu134e, Rps6ka-rs1, Rsk3, p90rsk, pp90rsk

    Protein Size: 733

    Molecular Weight

    81 kDa

    Gene ID

    20112

    NCBI Accession

    NM_011299, NP_035429

    UniProt

    Q9WUT3
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