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NFYA Protein (AA 1-318)

This Recombinant NFYA protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN1880589

Quick Overview for NFYA Protein (AA 1-318) (ABIN1880589)

Target

See all NFYA Proteins
NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Protein Type

Recombinant

Origin

  • 7
  • 2
  • 1
  • 1
Human

Source

  • 4
  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 1-318

    Purpose

    Recombinant Human Nuclear Transcription Factor Y Subunit α/NFYA

    Sequence

    MEQYTANSNS STEQIVVQAG QIQQQVQGQP LMVQVSGGQL ITSTGQPIMV QAVPGGQGQT IMQVPVSGTQ GLQQIQLVPP GQIQIQGGQA VQVQGQQGQT QQIIIQQPQT AVTAGQTQTQ QQIAVQGQQV AQTAEGQTIV YQPVNADGTI LQQVTVPVSG MITIPAASLA GAQIVQTGAN TNTTSSGQGT VTVTLPVAGN VVNSGGMVMM VPGAGSVPAI QRIPLPGAEM LEEEPLYVNA KQYNRILKRR QARAKLEAEG KIPKERRKYL HESRHRHAMA RKRGEGGRFF SPKEKDSPHM QDPNQADEEA MTQIIRVS

    Characteristics

    Recombinant Human Nuclear Transcription Factor Y Subunit α/NFYA is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser318) of Human NFYA.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Handling Advice

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    Storage

    4 °C/-20 °C/-80 °C

    Storage Comment

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

    Alternative Name

    Nuclear Transcription Factor Y Subunit alpha/nfya

    Background

    Nuclear Transcription Factor Y Subunit α (NFYA) is a member of the NFYA/HAP2 subunit family. NFYA founctions as a heterotrimeric transcription factor , which is composed of three components, NF-YA, NF-YB and NF-YC, binds to CCAAT motifs in the promoter regions in a variety of genes. NFYA forms a highly conserved transcription factor which stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.

    Molecular Weight

    33.9 kDa

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
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