OB Cadherin Protein (AA 23-617) (Fc Tag,His tag)
Quick Overview for OB Cadherin Protein (AA 23-617) (Fc Tag,His tag) (ABIN1880628)
Target
See all OB Cadherin (CDH11) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 23-617
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Purification tag / Conjugate
- This OB Cadherin protein is labelled with Fc Tag,His tag.
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Purpose
- Recombinant Human Cadherin-11/OB-Cadherin/CDH11 (C-Fc-6His)
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Sequence
- FAPERRGHLR PSFHGHHEKG KEGQVLQRSK RGWVWNQFFV IEEYTGPDPV LVGRLHSDID SGDGNIKYIL SGEGAGTIFV IDDKSGNIHA TKTLDREERA QYTLMAQAVD RDTNRPLEPP SEFIVKVQDI NDNPPEFLHE TYHANVPERS NVGTSVIQVT ASDADDPTYG NSAKLVYSIL EGQPYFSVEA QTGIIRTALP NMDREAKEEY HVVIQAKDMG GHMGGLSGTT KVMITLTDVN DNPPKFPQSV YQMSVSEAAV PGEEVGRVKA KDPDIGENGL VTYNIVDGDG MESFEITTDY ETQEGVIKLK KPVDFETKRA YSLKVEAANV HIDPKFISNG PFKDTVTVKI AVEDADEPPM FLAPSYIHEV QENAAAGTVV GRVHAKDPDA ANSPIRYSID RHTDLDRFFT INPEDGFIKT TKPLDREETA WLNITVFAAE IHNRHQEAKV PVAIRVLDVN DNAPKFAAPY EGFICESDQT KPLSNQPIVT ISADDKDDTA NGPRFIFSLP PEIIHNPNFT VRDNRDNTAG VYARRGGFSR QKQDLYLLPI VISDGGIPPM SSTNTLTIKV CGCDVNGALL SCNAEAYILN AGLSTVDDIE GRMDEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSREEMTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH
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Characteristics
- Recombinant Human Cadherin-11/ CDH11 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Phe23-Thr617) ofHuman CDH11 fused with a FC-6His tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Cadherin 11 (CDH11) (AA 23-617) protein (His tag)
CDH11 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Cadherin 11 (CDH11) (AA 54-617) protein (His tag)CDH11 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cadherin 11 (CDH11) (AA 54-617) protein (His tag)CDH11 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Cadherin 11 (CDH11) (AA 54-617) protein (His-DYKDDDDK-Strep II Tag)CDH11 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
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Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Storage
- 4 °C/-20 °C/-80 °C
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Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
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Alternative Name
- CDH11
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Background
- Cadherin-11, also known as OSF-4, Osteoblast cadherin and CDH11, is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
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Molecular Weight
- 93.5 kDa
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UniProt
- Q96CZ9
Target
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