Adrenoceptor alpha 1A (ADRA1A) (C-Term) Peptide
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- Target See all alpha 1 Adrenergic Receptor (ADRA1A) products
- alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LKSGLKTDKS DSEQVTLRIH RKNAPAGGSG MASAKTKTHF SVRLLKFSRE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADRA1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))
- Synonyms
- ADRA1C Peptide, ADRA1L1 Peptide, ALPHA1AAR Peptide, Adra1c Peptide, ALPHA-1A Peptide, alpha-1A Peptide, adrenoceptor alpha 1A Peptide, adrenergic receptor, alpha 1a Peptide, ADRA1A Peptide, Adra1a Peptide
- Background
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Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Alias Symbols: ADRA1C, ADRA1L1, ALPHA1AAR
Protein Size: 370 - Molecular Weight
- 40 kDa
- Gene ID
- 148
- NCBI Accession
- NM_033304, NP_150647
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