SET Domain and Mariner Transposase Fusion Gene (SETMAR) (C-Term) Peptide
SETMAR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183373
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for SET Domain and Mariner Transposase Fusion Gene (SETMAR) (C-Term) Peptide (ABIN2183373)
Target
SETMAR
(SET Domain and Mariner Transposase Fusion Gene (SETMAR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- FLQGKRFHNQ QDAENAFQEF VESQSTDFYA TGINQLISRW QKCVDCNGSY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SETMAR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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SET Domain and Mariner Transposase Fusion Gene (SETMAR) peptide
SETMAR Reactivity: Human, Cow Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
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Background
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This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.
Protein Size: 545 -
Molecular Weight
- 59 kDa
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Gene ID
- 6419
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NCBI Accession
- NP_001230652
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UniProt
- E7EN68
Target
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