SET Domain and Mariner Transposase Fusion Gene (SETMAR) (Middle Region) Peptide
SETMAR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671864
$160.46
Plus shipping costs $50.00
100 μg
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Quick Overview for SET Domain and Mariner Transposase Fusion Gene (SETMAR) (Middle Region) Peptide (ABIN5671864)
Target
SETMAR
(SET Domain and Mariner Transposase Fusion Gene (SETMAR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- VDPTYIGNIG RFLNHSCEPN LLMIPVRIDS MVPKLALFAA KDIVPEEELS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- SETMAR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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SET Domain and Mariner Transposase Fusion Gene (SETMAR) peptide
SETMAR Reactivity: Human, Cow Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
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Background
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This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Alias Symbols: Mar1, HsMar1, METNASE
Protein Size: 365 -
Gene ID
- 6419
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NCBI Accession
- NM_001243723, NP_001230652
Target
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