SET Domain and Mariner Transposase Fusion Gene (SETMAR) (Middle Region) Peptide
SETMAR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SETMAR products
- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VDPTYIGNIG RFLNHSCEPN LLMIPVRIDS MVPKLALFAA KDIVPEEELS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- SETMAR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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SET Domain and Mariner Transposase Fusion Gene (SETMAR) peptide
SETMAR Reactivity: Human, Cow Host: Synthetic BP, Imm
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
- Synonyms
- HsMar1 Peptide, METNASE Peptide, Mar1 Peptide, 5830404F24Rik Peptide, Etet2 Peptide, SETMAR Peptide, zgc:172212 Peptide, SET domain and mariner transposase fusion gene Peptide, SET domain without mariner transposase fusion Peptide, histone-lysine N-methyltransferase SETMAR Peptide, SETMAR Peptide, Setmar Peptide, LOC470738 Peptide, setmar Peptide, LOC703880 Peptide, LOC100447656 Peptide, LOC100586616 Peptide
- Background
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This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Alias Symbols: Mar1, HsMar1, METNASE
Protein Size: 365 - Gene ID
- 6419
- NCBI Accession
- NM_001243723, NP_001230652
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