RAR-Related Orphan Receptor C (RORC) (N-Term) Peptide
RORC
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183415
Quick Overview for RAR-Related Orphan Receptor C (RORC) (N-Term) Peptide (ABIN2183415)
Target
RORC
(RAR-Related Orphan Receptor C (RORC))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MDRAPQRQHR ASRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RORC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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Background
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RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.
Alias Symbols: NR1F3, RORG, RZR-GAMMA, RZRG, TOR
Protein Size: 518 -
Molecular Weight
- 58 kDa
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Gene ID
- 6097
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NCBI Accession
- NM_005060, NP_005051
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UniProt
- Q6I9R9
Target
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