RAR-Related Orphan Receptor C (RORC) (Middle Region) Peptide
RORC
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RORC products
- RORC (RAR-Related Orphan Receptor C (RORC))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RORC antibody (Catalog #: ARP33243_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RORC (RAR-Related Orphan Receptor C (RORC))
- Synonyms
- NR1F3 Peptide, RORG Peptide, RZR-GAMMA Peptide, RZRG Peptide, TOR Peptide, Nr1f3 Peptide, RORgamma Peptide, Thor Peptide, RAR related orphan receptor C Peptide, RAR-related orphan receptor C Peptide, RAR-related orphan receptor gamma Peptide, RORC Peptide, Rorc Peptide
- Background
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RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC129539, NR1F3, RORG, RZRG, TOR, RZR-GAMMA
Protein Interaction Partner: CHD4,EIF4EBP1,NCOA6
Protein Size: 497 - Molecular Weight
- 56 kDa
- Gene ID
- 6097
- NCBI Accession
- NM_001001523, NP_001001523
- UniProt
- B3KUU9
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