Mitochondrial Ribosomal Protein L2 (MRPL2) (N-Term) Peptide

Details for Product No. ABIN2183470, Supplier: Log in to see
Protein Name
  • L37mt
  • MRP-L2
  • MRP-L37
  • MRPL2
  • RPML2
  • MRP-L14
  • RPML14
  • CGI-22
  • Rpml14
  • mitochondrial ribosomal protein L37
  • mitochondrial ribosomal protein L2
  • MRPL37
  • MRPL2
  • Mrpl2
Protein Region
N-Term
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Blocked Antibody anti-MRPL2 antibody (Mitochondrial Ribosomal Protein L2) (N-Term) (ABIN2791668)
Sequence GGGHKQRYRM IDFLRFRPEE TKSGPFEEKV IQVRYDPCRS ADIALVAGGS
Characteristics This is a synthetic peptide designed for use in combination with anti-MRPL2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q.

Alias Symbols: MRP-L14, RPML14

Protein Size: 305
Molecular Weight 33 kDa
Gene ID 51069
NCBI Accession NM_015950, NP_057034
UniProt Q5T653
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.