Syntrophin, gamma 2 (SNTG2) (C-Term) Peptide
Quick Overview for Syntrophin, gamma 2 (SNTG2) (C-Term) Peptide (ABIN2183566)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- NVLWRFKFSQ LKGSSDDGKT RVKLLFQNLD TKQIETKELE FQDLRAVLHC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SNTG2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SNTG2 (Syntrophin, gamma 2 (SNTG2))
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Background
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This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
Alias Symbols: G2SYN, SYN5
Protein Size: 539 -
Molecular Weight
- 59 kDa
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Gene ID
- 54221
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NCBI Accession
- NM_018968, NP_061841
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UniProt
- Q9NY99
Target
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