Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) Peptide
CCR2
Reactivity: Human
Host: Synthetic
BP, WB
Quick Overview for Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) Peptide (ABIN2183653)
Target
CCR2
(Chemokine (C-C Motif) Receptor 2 (CCR2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- RSRFIRNTNE SGEEVTTFFD YDYGAPCHKF DVKQIGAQLL PPLYSLVFIF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CCR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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Background
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This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Alias Symbols: CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
Protein Size: 360 -
Molecular Weight
- 39 kDa
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Gene ID
- 729230
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NCBI Accession
- NM_001123396, NP_001116868
Target
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