Chemokine (C-C Motif) Receptor 2 (CCR2) (C-Term) Peptide
CCR2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CCR2 products
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FTIMIVYFLF WTPYNIVILL NTFQEFFGLS NCESTSQLDQ ATQVTETLGM
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CCR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Synonyms
- CC-CKR-2 Peptide, CCR-2 Peptide, CCR2A Peptide, CCR2B Peptide, CD192 Peptide, CKR2 Peptide, CKR2A Peptide, CKR2B Peptide, CMKBR2 Peptide, MCP-1-R Peptide, ACKR5 Peptide, CKRX Peptide, CRAM Peptide, CRAM-A Peptide, CRAM-B Peptide, HCR Peptide, Cc-ckr-2 Peptide, Ccr2a Peptide, Ccr2b Peptide, Ckr2 Peptide, Ckr2a Peptide, Ckr2b Peptide, Cmkbr2 Peptide, mJe-r Peptide, C-C motif chemokine receptor 2 Peptide, C-C motif chemokine receptor like 2 Peptide, chemokine (C-C motif) receptor 2 Peptide, CCR2 Peptide, CCRL2 Peptide, Ccr2 Peptide, LOC484790 Peptide
- Background
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This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.
Alias Symbols: CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2
Protein Size: 374 - Molecular Weight
- 42 kDa
- Gene ID
- 1231
- NCBI Accession
- NM_000647, NP_000638
- UniProt
- P41597
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