Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) Peptide
F2RL1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2184390
Quick Overview for Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) Peptide (ABIN2184390)
Target
F2RL1
(Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- SAYVLMIRML RSSAMDENSE KKRKRAIKLI VTVLAMYLIC FTPSNLLLVV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-F2RL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
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Background
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Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.
Alias Symbols: GPR11, PAR2
Protein Size: 397 -
Molecular Weight
- 44 kDa
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Gene ID
- 2150
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NCBI Accession
- NM_005242, NP_005233
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UniProt
- P55085
Target
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