Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) Peptide
F2RL1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all F2RL1 products
- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VSHDFRDHAK NALLCRSVRT VKQMQVSLTS KKHSRKSSSY SSSSTTVKTS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-F2RL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
- Synonyms
- par2 Peptide, GPR11 Peptide, PAR2 Peptide, Gpcr11 Peptide, PAR-2 Peptide, Par2 Peptide, Par-2 Peptide, Proteinase-activated receptor 2 Peptide, F2R like trypsin receptor 1 Peptide, coagulation factor II (thrombin) receptor-like 1 Peptide, par2 Peptide, F2RL1 Peptide, F2rl1 Peptide
- Background
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Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.
Alias Symbols: GPR11, PAR2
Protein Interaction Partner: CAPN1,CAPN2,CBL,COPS5,CTSG,ELANE,F2,GPRASP1,PLG,PRTN3,ST14,Cbl,UBC
Protein Size: 397 - Molecular Weight
- 44 kDa
- Gene ID
- 2150
- NCBI Accession
- NM_005242, NP_005233
- UniProt
- P55085
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